Sentence examples for principal cell cycle from inspiring English sources
Investigators have also employed late fetal and neonatal (and some adult) rat CM after infection with recombinant adenoviruses to alter principal cell cycle regulators [7]; however, adenovirus gene transfer vectors can induce cell cycle dysregulation and inappropriate expression of cyclin proteins, which complicate the interpretation of published studies [12].
We show that Rb, independent of both p107 and p130, acts both as a principal regulator of cell cycle progression through G1 and as a modulator of the transition from immature to mature CM.
Cyclin D1 is a principal player in cell cycle progression [ 51] and a key molecular target of NF- κB [ 46].
Thus, the analysis revealed the principal pathways of cell cycle, mitosis, and chromosome segregation, as well as apoptosis and cell death.
More precisely, the major purpose of this article is to shed light on the principal mechanism organizing the cell cycle of Saccharomyces cerevisiae by using a novel approach based on the notion of causal membership.
Taken together, the pocket protein gene family functions as the principal regulator of VCS/trabecular myocyte cell cycle arrest.
Indeed, reduced GABA conductance was shown to advance spiking of principal cells within the cycle in slices of the rat somatosensory cortex (Morita et al. 2008).
From the gene perspective this was reflected in one main branch associated with cell cycle and cell proliferation, and the second including two principal subclusters associated on the one hand with RNA binding and processing, and on the other with core B-cell-associated genes (Fig. 2b; Additional file 8).
This prevents CDK4 from adding phosphate residues to its principal substrate, retinoblastoma (pRb) protein blocking cell cycle G1/S transition.
The SBF (Swi4p-Swi6p) complex, in concert with MBF (Mbp1-Swi6p), is the principal transcriptional regulator of the yeast cell cycle [ 26].
The principal biochemical species of the G2/M phase cell cycle are the M phase promoting factor (MPF), Cdc25 and Wee1.
