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A partial cDNA fragment of the Cryptococcus neoformans homologue of the main cell cycle control gene CDC28/cdc2 was isolated using degenerate primer RT-PCR.
This retrospective study was designed to correlate regression, persistence and progression of biopsy-proven LSIL with patients' age, HPV genotypes and immunohistochemical expression of the main cell cycle regulating proteins: p53, pRb, p16, and Ki-67.
Cell cycle proteins (cyclins), CDKs, and CDKIs are the main cell cycle regulators during tumor progression [ 25].
Our model rediscovers the main cell cycle transcription factors and provides new insights into the regulatory mechanisms.
This is the same sequence specificity as assigned to the CcrM methylase (the main cell cycle regulator).
The main cell cycle effect of these drugs (at 2 x IC50) was a slowdown in S-phase traverse during which most but not all of the apoptosis appeared to occur.
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Many genes regulated by cisplatin belong to two main groups: cell cycle and proliferation.
The DEGs linked to cell proliferation were involved in three main phenomena: cell cycle arrest impairment, cell proliferation enhancement and apoptosis blocking (Table 2).
The main cell division and cell cycle was in both communities were the control of cell elongation division cycle, and the particular enzyme involved is the endonuclease III (EC 4.2.99.18).
Such XNXK cells, also previously observed in the bloodstream cells depleted of TbAUK1 [5], representing one of the main distinctions in cell cycle regulation between the bloodstream and procyclic forms (see Discussion).
S-phase duration is the main target of cell cycle regulation in neural progenitors of developing ferret neocortex.
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