Sentence examples for maintaining normal heart from inspiring English sources

These findings not only highlight the importance of these cardiac-specific genes in maintaining normal heart development and functions, but may also provide novel gene targets for uncovering heart disease mechanisms.

In contrast, many genes involved in maintaining normal heart functions such as cardiac contraction and heart rate regulation were down-regulated.

At higher mercury exposures, children were less capable of maintaining normal heart rate variability, which is a risk factor for development of heart disease.

These data suggest that ilk/mys function is necessary for establishing and maintaining normal heart structure and function, and appropriate fine-tuning of this pathway can retard the age-dependent decline in cardiac performance and extend lifespan.

The expression patterns of ILK and β1-integrin in Drosophila hearts suggest a possible functional requirement for the β1-integrin/ILK pathway in maintaining normal heart structure and function.

Taken together, these data demonstrate that supra- or subphysiological levels of ROS in PCs adversely affect cardiac rhythm and morphology, suggesting that physiological levels of ROS within PCs are critical for their paracrine role in maintaining normal heart function.

In the down-regulated gene group, genes were identified that were related to biological processes that maintain normal heart cell function, including cardiac contraction and heart rate regulation, consistent with the decreased cardiac function of ICM patients found clinically.

Simulations presented in Figure 6, 7 show considerably diminished energetic stability in the no-CK system, and thus demonstrate significant roles of the creatine kinase system in maintaining normal function in the working heart.

Conditional cardiac-specific ablation of MFN1 and MFN2 in the adult murine heart has been reported to result in a severe lethal dilated cardiomyopathy after 6 8 weeks, a finding which was associated with mitochondrial fragmentation and impaired mitochondrial respiration, implicating a role for the mitofusins in maintaining normal mitochondrial function in the adult heart (Chen et al., 2011).

When it gets hotter than 35 °C, people have difficulty maintaining normal body temperature, putting strain on the heart.

Previous studies have suggested that upregulation of the GLUT1 isoform is responsible for maintaining normal levels of glucose transport into the heart.