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These data indicate that precision-cut tissue slices from transgenic mice offer a novel in vitro method for toxicity evaluation while maintaining normal cell heterogeneity.
Removal of vascular smooth muscle cells (SMC) from their native environment alters the biochemical and mechanical signals responsible for maintaining normal cell function, causing a shift from a quiescent, contractile phenotype to a more proliferative, synthetic state.
Maintaining normal cell morphology may also be essential for differentiation.
This result strongly suggested that the ACTN4 is essential for maintaining normal cell traction force.
As shown in Figure 6, ACTN4 KD fibroblasts proliferated significantly slower compared to the WT ACTN4 fibroblasts, suggesting that ACTN4 is required for maintaining normal cell division.
This result suggests the ACTN4 is essential for maintaining normal cell motility, and thus we sought to examine the various cell biochemical aspects of migration.
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Dimension sensing may be involved in guiding cell migration for both physiological functions and tissue engineering, and for maintaining normal cells in their home tissue.
Primary rat Schwann cells can be passaged indefinitely in culture while maintaining normal cell-cycle checkpoints [4].
This complexity helps maintain normal cell function in response to diverse perturbations.
The devastating disease in mother and son was caused by a genetic mutation in the RB1 tumor suppressor gene that, when unaffected, maintains normal cell division.
Apoptosis is a highly regulated process by which excessive cells are eliminated in order to maintain normal cell development and tissue homeostasis.
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maintaining normal lung
maintaining normal nerve
maintaining normal regulation
maintaining normal insulin
maintaining normal tumor
maintaining normal metabolism
maintaining normal weight
maintaining normal function
maintaining normal activity-dependence
maintaining normal growth
maintaining normal operation
maintaining normal motor
maintaining normal physiology
maintaining normal intine
maintaining normal body
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