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PCNA functions in cell cycle progression and serves as an attractive assay of cell proliferation; Ki-67 is a nuclear protein that is expressed in proliferating cells and may be required for maintaining cell proliferation.
Our organ-culture results indicated that BMP4 regulates HERS formation via harmonious interactions with its own antagonist, noggin, by preventing elongation and maintaining cell proliferation.
Transformation hampers progression of malignant cells towards terminal osteoblastic differentiation while maintaining cell proliferation.
These results suggest that CIAPIN1 overexpression may be essential for maintaining cell proliferation as well as cell survival in HCC.
Interestingly, 10-7 M genistein treatment over 6-9 days was more robust in maintaining cell proliferation than a physiological concentration of E2.
It is essential for maintaining cell proliferation [ 16, 17] and inhibition of eIF5A-2 has been shown to suppress cell proliferation in many tumors [ 18, 19].
Similar(52)
In fibroblasts, FGFs bind to FGFRs and activate the intracellular ERK1/2 cascade to maintain cell proliferation.
Adrenomedullin also maintains cell proliferation of breast tumour cell lines T47D in serum-free conditions (Martinez et al, 2002).
At this time unoccupied TRs are critical factors that generally maintain cell proliferation and prevent differentiation [19,27].
Alternatively, because the proliferative response is suppressed in LAPE cells [ 5] (Fig. 3), increased growth factor signaling could result from a feedback mechanism to maintain cell proliferation.
It is also possible that FGF signalling maintains cell proliferation and growth within the proepicardium and does not influence proepicardial/epicardial cell identity (Torlopp et al., 2010).
Related(20)
maintaining cell expansion
sustaining cell proliferation
safeguarding cell proliferation
maintaining cell cycle
maintaining cell division
maintaining cell motility
maintaining cell integrity
maintaining cell physiology
maintaining cell surface
maintaining cell pluripotency
maintaining cell specificity
maintaining cell wall
maintaining cell identity
maintaining cell adhesion
maintaining cell shape
maintaining cell side
maintaining cell viability
maintaining cell homeostasis
maintaining cell membrane
maintaining cell survival
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