Sentence examples for main functional effect from inspiring English sources

This indicates that although a large fraction of the differentially expressed genes are located in the same chromosomal regions, the main functional effect is due to genes from multiple other chromosomes.

We could demonstrate that the main functional effect of activating these surface EGFRs in breast cancer cells is stimulation of migration.

The variant of this SNP was postulated to increase DNA methylation based on its demonstrated decreasing effect on gene transcription (Artiga et al., 1998), the main functional effect of DNA methylation (Lindahl, 1981).

In contrast, however, there is no affect of TNK2 siRNA on proliferation or apoptosis, which is in agreement with our findings that the main functional effect of EGFR activation in these breast cancer cells is stimulation of motility.

Altogether the data point to RIPK1 as the main functional target mediating the protective effect of pazopanib.

Owing to the ease of visualization and interpretation, non-overlapping clustering methods can quickly generate a global overview of the dataset, revealing the main expression and functional effects among the different biological samples in the dataset2.

Following a diagnosis of PD, NICE considers the management in 3 main tiers: management of early PD (functional effect of disease apparent), management of late PD (motor complications), and surgical management.

This effect was noted for GLA, a main functional component in licorice root.

Taking into account these substantial differences in proteome modulation following infection, we compared the DAPs in the GCi and WTi groups (Fig. 7d) to highlight the effect of the genotype over infection, revealing that the main functional categories were related to translation (11%) and transport (9%).

Predicting the functional effect of amino acid substitutions and indels.

The modules are grouped in three main functional blocks.