Sentence examples for major functional effect from inspiring English sources

So far, a major functional effect on the NF-κB pathway has only be shown for the p.Leu1007fsX1008 variant 6.

This data suggests that whilst IP receptors may play a small role in the effects of GW0742 in some vessels, the major functional effect of this drug is, on the whole, independent of IP receptors.

Non-synonymous transversions at first and second codon positions result primarily in amino acid replacements with radical physico-chemical differences and major functional effects, but there is a strong correlation between dNTV12 and overall amino acid replacement rates (r2 = 0.95; p<<0.001; Figure S10).

Together the lack of significant effect of T1410 mutation on dimerization and kinase activity indicate that it does not have a major functional consequence on LRRK2's phosphorylating activity towards other substrates.

The global effects on the major functional categories Zn and Cd treatments had on the two strains were assessed by comparing the distributions of CDS fold changes classified by COG categories and by comparing COG classes to which the most significantly regulated genes (FDR < 0.1 in at least one comparison) were associated (Additional file 9).

Since the carboxyl group is one of the major functional groups in agricultural wastes, it will have an effect on the adsorption capacity according to the dye class.

A major functional distinction between Ssa1 and Ssa2 exists in their effects on yeast prion propagation.

The major findings were: (1) annotations of disease-causation provide a good approximation of functional effect.

The major conclusion is that a combined standing/stepping training protocol in severe spinal cord contusion injury had a significantly beneficial functional effect in the irradiated rats.

The other major functional changes are related to navigation.

"The major functional areas have been cloudified," he says.