lose efficacy

USAGE SUMMARY

The phrase "lose efficacy" is correct and usable in written English.
It can be used when discussing the reduction in effectiveness or potency of something, such as a medication or strategy. Example: "Over time, the medication may lose efficacy, requiring a dosage adjustment."

✓ Grammatically correct

Science

News & Media

Human-verified examples from authoritative sources

Exact Expressions

30 human-written examples

They all lose efficacy over time.

The Washington Post

These factors lose efficacy when gated neighborhoods are selected and surrounding facilities are distributed far away.

Cities

Antibodies developed during HIV-1 infection lose efficacy as the viral spike mutates.

Cell

"Standard vaccines rapidly lose efficacy, because the influenza virus is constantly mutating into new, unpredictable strains.

Independent

The mutation and resultant adaptability of HIV-1 reverse transcriptase (RT) present a major challenge to the design of the effective antiviral strategies because many initially potent drugs lose efficacy over time.

Antiviral Research

The measurement result will finally lose efficacy due to these errors.

Journal of Modern Transportation

Human-verified similar examples from authoritative sources

Similar Expressions

30 human-written examples

That pill gradually loses efficacy and can be taken at most three days after sex.

The New York Times

Multidrug-resistant bacteria are a major threat to human health, but broad-spectrum antibiotics are losing efficacy.

Chem

But it is now known that when the relevant variables are as closely related as frequency, age of acquisition (AoA), and familiarity, regression analysis loses efficacy.

Journal of Neurolinguistics

Yale: 44 eyes of 35 patients, ≥18 years of age, with open-angle glaucoma (primary open-angle, pseudoexfoliation, or pigmentary glaucoma), uncontrolled on maximum tolerable medical therapy, underwent an initial 360-degree SLT (SLT1), which was successful for ≥6 months, but eventually lost efficacy and was followed by a repeat 360-degree SLT (SLT2).

Yale University

The TB Alliance and MMV are searching for drugs to augment current treatments for tuberculosis and malaria that are losing efficacy.

Science Magazine

Expert writing Tips

Best practice

When discussing treatments or interventions, clarify the timeline over which they "lose efficacy". This provides important context about their long-term effectiveness.

Common error

Avoid exaggerating the loss of efficacy. Instead of saying something completely "loses efficacy", specify the degree or conditions under which the efficacy decreases. This adds nuance and accuracy to your writing.

Linguistic Context

The phrase "lose efficacy" functions as a verb phrase where "lose" is the verb and "efficacy" is the noun functioning as the direct object. Ludwig AI's analysis confirms its grammatical correctness and usability.

Expression frequency: Common

Frequent in

Science

68%

News & Media

24%

Academia

8%

Less common in

Formal & Business

0%

Wiki

0%

Reference

0%

Ludwig's WRAP-UP

In summary, the phrase "lose efficacy" is a grammatically sound and commonly used expression to describe a decline in effectiveness or potency, as affirmed by Ludwig AI. Predominantly found in scientific and news contexts, it maintains a neutral to formal tone. When using this phrase, ensure you specify the factors contributing to the loss and avoid overstating the degree of ineffectiveness. Consider using alternatives like "diminish in effectiveness" or "decrease in potency" for variety. Remember that context is key to clearly articulate the situations when something "loses efficacy".

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

become less effective

Uses a more descriptive phrase to convey the reduction in effectiveness.

diminish in effectiveness

Replaces 'lose' with 'diminish', focusing on the gradual reduction of effectiveness.

decrease in potency

Substitutes 'lose' with 'decrease', highlighting a reduction in strength or potency.

experience diminished effect

Highlights the experience of a lessened effect or outcome.

see a drop in efficacy

Emphasizes a measurable decrease in effectiveness.

wane in influence

Changes the focus to influence, suggesting a decline in persuasive power.

weaken in impact

Replaces 'lose' with 'weaken', emphasizing a reduced effect or influence.

fade in effectiveness

Suggests a gradual and subtle decline in how effective something is.

decline in performance

Shifts the focus to performance, implying a reduction in the ability to function effectively.

suffer reduced impact

Focuses on the negative consequence of reduced effectiveness.

FAQs

How can I use "lose efficacy" in a sentence?

You can use "lose efficacy" to describe how something becomes less effective over time, such as "The drug may "lose efficacy" with prolonged use" or "The strategy began to "lose efficacy" as the market changed".

What's a more formal way to say "lose efficacy"?

More formal alternatives include "diminish in effectiveness" or "experience a reduction in potency". For example, "The treatment may "diminish in effectiveness" over time".

Is it correct to say "loses efficacy"?

Yes, "loses efficacy" is grammatically correct. You would use "loses" with a singular subject, such as "The vaccine "loses efficacy" after a few years".

What factors can cause something to "lose efficacy"?

Several factors can cause something to "lose efficacy", including resistance to drugs, changes in environmental conditions, or the evolution of a virus. For instance, "Antibiotics can "lose efficacy" due to antibiotic resistance".