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By September, his problem had made its way into the liberal Copenhagen daily Politiken, and was promptly co-opted by the conservative daily Jyllands-Posten, whose arts editor — now on "indefinite leave" — asked forty artists to "test the limits of expression" by drawing pictures of Muhammad.
The result is not just a great book, but a valuable document of the limits of expression in the mid-sixties U.S.S.R. Reading though the text in bold, some of the censors' cuts come as no surprise: "I hope Stalin croaks!," Kuznetsov's grandfather says on page 62.
As described above, the CZ and NZ are delineated by the limits of expression of the Purkinje cell stripe marker HSP25 [31].
Consequently, their ventral limits of expression are determined by Shh signalling.
This presents a problem, since the authors' hypothesis of "reversible" and "irreversible" gene expression change would lead one to expect that never and current smokers would define the limits of expression, with former smokers falling somewhere within this continuum.
The regulatory domains have been roughly defined by mutant lesions (Lewis, 1978), and by enhancer traps in the BX-C, which show different anterior limits of expression (Bender and Hudson, 2000).
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The caudal limit of cSox2 expression coincides with that of the region competent for proventricular differentiation and to the rostral limit of expression of CdxA, a chicken member of the caudal-related homeobox gene family (Ishii et al, 1998).
Upregulation of these genes might not exceed a certain limit of expression because protein concentration will quickly increase in the small intracellular compartment, where they act.
For mespa we used a grid to measure the distance between the posterior tip of the embryo and the posterior limit of expression.
Its anterior limit of expression is more graded and less well defined and ectopic anterior margin in the adult wing can only rarely be observed.
According to the threshold model, all birds have migratory activity, although in residents this is below a limit of expression or detection.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com