in close combination

USAGE SUMMARY

The phrase "in close combination" is correct and usable in written English.
It can be used to describe two or more elements that are closely linked or working together in a specific context. Example: "The two chemicals react in close combination to produce a more effective solution."

✓ Grammatically correct

Science

News & Media

Human-verified examples from authoritative sources

Exact Expressions

4 human-written examples

After returning to China in 1934, he continued to conduct in-depth research on the nutritive value of soybean protein in close combination with the national conditions.

Protein & Cell

"Our party's major goal is to support progressive national traditions in close combination with every progressive idea appearing in the world," Dagvasurengiyn Ganbold, chairman of the party, said in a June interview with Radio Ulan Bator.

Los Angeles Times

Alternatively, it might be more beneficial for some individuals to drive the intervention strategy towards basic joint mobility and the practice of precise motor control in close combination with targeted drills to relieve pain symptoms.

BMC Musculoskeletal Disorders

Although PC emerged in close combination with the NICUs [ 47], to encourage incorporation of the process in the family environment, the possibility of PC taking place in the home (at least on a temporary basis) was considered [ 32, 48].

BMC Pediatrics

Human-verified similar examples from authoritative sources

Similar Expressions

56 human-written examples

In educational sociology, scholars have made a closer combination between social stratification and education supply.

The Journal of Chinese Sociology

Messi, in his fourth game back after a long injury layoff, worked a one-two passing combination in close quarters with Cesc Fabregas to manufacture Barcelona's best chance in the 59th, but goalkeeper Keylor Navas saved Messi's shot.

Independent

The φ and ψ angles of a residue cannot adopt all values due to backbone intrinsic torsion propensities and attractive and repulsive interactions of atoms that are in close proximity for certain combinations of these two angles.

Plosone

Larkin et al.[ 22] argue that the continued presence of HSBs in all species may indicate a selective advantage to the retention of gene combinations in close proximity.

BMC Genomics

This upregulation correlated with our previous observations, signifying the importance of activating specific TLR agonist combinations in close proximity and the effect of synergistic interactions on innate immune cells.

ACS Central Science

We mapped the activity of our compounds to gene expression for specific immune-related functions, such as TH1 and TH2 linked responses, to observe if activating specific agonist combinations in close proximity upregulated a response and to what extent.

ACS Central Science

None of these pulsation frequencies or their low-order linear combinations are in close resonance with the orbital frequency.

Princeton University

Expert writing Tips

Best practice

When using "in close combination", ensure that the elements you are combining genuinely benefit from their proximity and interaction. Avoid using it for elements that are merely placed near each other without any functional relationship.

Common error

Avoid using "in close combination" when simply describing items that are near each other without a functional or interactive relationship. For example, instead of saying "The book and the pen were in close combination on the desk", use a simpler phrase like "The book and pen were on the desk together."

Linguistic Context

The phrase "in close combination" primarily functions as a prepositional phrase, modifying a verb or noun to indicate how elements are related or used. Ludwig AI supports this understanding through diverse examples of its use.

Expression frequency: Rare

Frequent in

Science

70%

News & Media

20%

Formal & Business

10%

Less common in

Encyclopedias

0%

Wiki

0%

Reference

0%

Ludwig's WRAP-UP

In summary, "in close combination" is a grammatically correct phrase that describes elements working together intimately. As confirmed by Ludwig AI, it's most commonly found in scientific and technical contexts. While the phrase is valid, it's essential to ensure that its use accurately reflects a genuine interaction between elements, as opposed to mere proximity. Consider alternatives like "in close association" or "in tight conjunction" to achieve the desired emphasis.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

in close association

Emphasizes the connection or relationship between elements.

in tight conjunction

Highlights the simultaneous or linked occurrence of elements.

in close coordination

Focuses on the organized and harmonious working together of elements.

in intimate union

Suggests a very deep and inseparable connection.

in immediate proximity

Stresses the physical closeness or nearness of elements.

in a closely-knit arrangement

Highlights the careful planning and tight integration of elements.

working synergistically

Focuses on the combined effect being greater than the sum of individual effects.

integrated seamlessly

Emphasizes the smooth and effortless combination of elements.

acting in concert

Stresses the harmonious and coordinated action of multiple agents.

mutually reinforcing

Highlights how elements strengthen and support each other.

FAQs

How can I use "in close combination" in a sentence?

Use "in close combination" to describe elements working together intimately. For example: "The scientists used drug A "in close combination" with drug B to enhance the therapeutic effect."

What phrases are similar to "in close combination"?

Alternatives include "in close association", "in tight conjunction", or "in close coordination", depending on the specific nuance you want to convey.

Is "in close combination" formal or informal?

"In close combination" is generally considered a more formal expression, suitable for academic, scientific, or professional contexts. Simpler alternatives might be preferred in informal settings.

How does "in close combination" differ from "in close proximity"?

"In close proximity" refers to nearness in space or time, while "in close combination" implies that the elements are not only near but also interacting or working together. They aren't always interchangeable.