Dictionary
homologous
adjective
Showing a degree of correspondence or similarity.
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The word "homologous" is correct and usable in written English.
It can be used to describe two or more organisms or structures that have similar characteristics, or when referring to the comparison of a gene or other entity from different species. For example, "The kidneys of a human and a rat are homologous."
Exact(60)
One component of the orthologous (homologous) proteins in both species retains an activity-function homology related to visceral mesoderm specification but another component (not the homeodomain) has diverged.
But are these genes unique to the fly, or do homologous genes determine the development of a human embryo?The answer to that question has had to wait for the invention of recombinant DNA technology which has made it possible to isolate, copy and amplify genes from a fly and to re-introduce them into a mouse, or vice versa.
When geneticists replaced one of the mutant fly genes by its homologous mouse gene the fly developed normal flies' eyes and not mouse eyes.
Similarly, a mouse which had its own gene controlling development of the eye replaced by the homologous fly gene developed a normal mouse eye.
In meiosis the two chromatids making up each chromosome remain together, so that whole chromosomes are separated from their homologous partners.
For instance, Portuguese men-of-war and their kin (some hydrozoan coelenterates) look and act like single individuals, yet their components develop as genetically identical units, each homologous to a whole jellyfish or polyp.
Polyploids with three, five, or some other odd-number multiple of the basic chromosome number are sterile, because the separation of homologous chromosomes cannot be achieved properly during formation of the sex cells.
Thus, a bird's wing is homologous to a bat's wing insofar as both are forelimbs, but they are not homologous as wings.
Just after Cuvier's classification, the French naturalist Étienne Geoffroy Saint-Hilaire outlined the importance of homologous structures.
Polyploids with odd numbers of sets (e.g., triploids) are sterile, because homologous chromosomes pair only two by two, and the extra chromosome moves randomly to a cell pole, resulting in highly unbalanced, nonfunctional meiotic products.
Sometimes it is unclear whether similarities in structure in different organisms are analogous or homologous.
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