Exact(8)
Many genes with unknown function were detected, which also respond to other abiotic stresses.
The most striking feature of this collection of genes is the dominance of genes with unknown function and TEs.
In contrast, highly expressed or regulated genes with unknown function can be further studied in identifying pathogenicity factors.
With the recently sequenced Babesia bovis genome, a large pool of genes with unknown function was identified.
Furthermore, 564 genes (13.9%) had a "general function" prediction, 270 genes with unknown function (6.65%) and 4177 genes (53.72%) were not assigned to any COG category.
Among the shared genes with unknown expression at the mRNA level in mice thyroid tissue, all but one (Klk1b21) had a value higher than 6.8.
The largest group contained genes with unknown functions such as expressed proteins, hypothetical proteins, and uncharacterized proteins (Additional file 3: Table S2).
Both studies revealed an unexpected high proportion of genes with unknown functions among the regulated genes.
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