Ai Feedback
Exact(5)
The BshC crystals used in this study were grown in the presence of 200 mM citrate, and electron density corresponding to a citrate molecule was observed within the canonical Rossmann fold active site.
Four heme superfamilies arose independently during evolution, which differ in overall fold, active site architecture and enzymatic activities.
Four heme peroxidase superfamilies (peroxidase catalase, peroxidase cyclooxygenase, peroxidase chlorite dismutase and peroxidase peroxygenase superfamily) arose independently during evolution, which differ in overall fold, active site architecture and enzymatic activities.
The review highlights the diversity in enzyme fold, active site architecture, and metal coordination that has evolved to catalyze this particular reaction.
Description of their overall fold, active site architecture and typical sequence patterns.
Similar(55)
Properly folded active insect AFP was only detected when signal sequences were used to target proteins to the endoplasmic reticulum for secretion into the hemolymph.
Compound 9 was found to be several hundred fold more active than standard D-Saccharic acid 1,4-lactone (IC50 = 45.75 ± 2.16 μM).
Interestingly, only fragments with precise amino acid residue numbers were able to fold into active holoenzymes in E. coli.
This may indicated a marked superiority of N-lobe over the full-length cLf and C-lobe in treatment of infected cells, with N-lobe being three- and four-fold active than the full-length cLf and C-lobe, respectively.
Both SMT19969 and fidaxomicin generally were 4- to 16-fold more active than vancomycin and 2- to 8-fold more active than metronidazole against C. difficile strains.
In addition, they were up to 3.6-fold more active on Avicel at 50 65°C and up to 2.5-fold more active on IL-Avicel at 50 65°C compared to their counterparts expressed in S. cerevisiae.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com