He called the idea fetal programming.
Pregnancy is a critical time for fetal programming of hypertension.
IVF alters fetal programming, with consequences for physical functioning.
This finding may have implications for fetal dysmorphogenesis and in fetal programming for adulthood disease.
Preeclampsia alters fetal programming and results in long-term metabolic consequences in the offspring.
Accordingly, disruptions in this pathway affect placental development and function leading to altered fetal programming.
Importantly, there are increasing concerns that assisted reproductive technologies cause aberrant epigenetic profiles in embryos leading to abnormal fetal programming.
Our results show that maternal overweight influences intrauterine growth pattern and therefore fetal programming sex-specific during the last 6 weeks of gestation.
The evidence for fetal programming is clear.
In my next blog, we will begin to look at what we know about the relation between fetal programming, fetal impacts, postnatal behavior, and mental illness.
The concept of fetal programming, of the developmental origins of health and disease, came out of the Dutch "Hunger Winter" -- a startling episode in science and history.
