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This fetal hemoglobin effectively counteracts the effects of the sickle mutation.
Bauer, D. E. & Orkin, S. H. Update on fetal hemoglobin gene regulation in hemoglobinopathies.
Wienert, B. et al. KLF1 drives the expression of fetal hemoglobin in British HPFH.
Masuda, T. et al. Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin.
Shortly after birth, all but 1percentt of fetal hemoglobin is replaced by adult hemoglobin.
Reawakening fetal hemoglobin: prospects for new therapies for the beta-globin disorders.
Fessas, P. & Stamatoyannopoulos, G. Hereditary persistence of fetal hemoglobin in Greece.
Huang, P. et al. Comparative analysis of three-dimensional chromosomal architecture identifies a novel fetal hemoglobin regulatory element.
Bauer, D. E. et al. An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level.
Giglioni, B. et al. A molecular study of a family with Greek hereditary persistence of fetal hemoglobin and β-thalassemia.
Xu, J. et al. Correction of sickle cell disease in adult mice by interference with fetal hemoglobin silencing.
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CEO of Professional Science Editing for Scientists @ prosciediting.com