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We used a 'two-hit' protocol to induce ALI in rabbits that showed extensive edema in the alveolar lumina, marked infiltration of neutrophils in the lung tissue, fibrin deposition in alveolar space, and destruction of pulmonary architecture, culminating in severe hypoxemia.
In contrast, extensive edema and neutrophilic and lymphocytic infiltration were observed in lung, liver, and spleen recovered from mice vaccinated with S50, S50 + MPLA, or S50 + E0.
Unlike the treated mice, control mice demonstrated thick epidermis with extensive edema as illustrated by cell spongiosis, high cellularity and infiltrating monocytes (Figure 2C).
Pathologic examination showed a central mucosal necrotic lesion along with hemorrhage and extensive edema.
Exploratory laparotomy revealed extensive edema of the cecum with mesenteric lymphadenopathy.
Patients with cutaneous anthrax may have fever, extensive edema, and other systemic signs.
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Histological results showed that extensive interstitial edema and infiltration of inflammatory cells occurred in injured lungs in the TBI + veh groups, but little interstitial edema and infiltration of inflammatory cells were observed in the TM-1 treated groups.
Note the extensive paraventricular edema.
On the other hand, all surviving MO1-only injected embryos showed extensive pericardial edema and other malformations by 4 dpf (Fig. 4D).
Many patients in the ICU have extensive subcutaneous edema.
Patient 1 manifested extensive, painless edema in the left thigh at the subcutaneous injection site.
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