Sentence examples for extensive bile from inspiring English sources

Other authors also showed that intrahepatic cholestasis in PQ poisoning in humans is secondary to extensive bile duct injury [31], [32].

Extensive bile duct proliferation is a key feature of the tissue reaction to clinical and experimental forms of liver injury.

The absence of VDR led to a strong increase in plasma bile acids and aminotransferases after BDL, further suggesting extensive bile spillover and subsequent increased hepatic toxicity.

There was marked architectural distortion of lobular structure and extensive bile duct proliferation infiltrating into hepatocytes with periportal fibrogenesis and occasional fibrogenesis in the parenchymal area, suggesting activation of HSCs.

Extensive bile duct proliferation is a key feature of the tissue reaction to clinical and experimental forms of liver injury and in many cases, this proliferation may affect liver function [ 1, 2].

Finally, the extensive variation of bile salt structures across vertebrate species predicts that protein receptors that bind bile salts will also show variation in structure and ligand-binding specificity.

In normal physiology, 18 F-fluoroacetate is not a functional analogue of 11C-acetate; 18F-fluoroacetate has a longer blood half-life, a rapid liver clearance and low myocardial uptake, extensive excretion into bile and urine, and suffers from skeletal defluorination resulting in skeletal uptake of the formed 18F-fluoride [79].

Another way that the gut microbiota influences the metabolic state of the host is through an extensive involvement in bile acid homeostasis [ 75].

An additional set of samples analyzed were from an extensive collection of bile samples of the late G.A.D. Haslewood, donated to the University of California - San Diego.

Current data supports the extensive interplay between bile acid-mediated signaling and insulin signaling in the regulation of lipid and nutrient metabolism in the liver.

The prospects for other bacterial enzymes that may be tractable for therapeutic benefit are extensive and include bile salt hydrolases, which have been manipulated experimentally to favorably influence lipid metabolism, weight gain and cholesterol levels in the host [ 7].