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Cockroaches have acinar salivary glands that consist of secretory acini and an extensive duct system [ 1, 2](see Fig. 1a).
The cockroach salivary gland consists of secretory acini with peripheral ion-transporting cells and central protein-producing cells, an extensive duct system, and a pair of reservoirs.
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Other authors also showed that intrahepatic cholestasis in PQ poisoning in humans is secondary to extensive bile duct injury [31], [32].
Extensive bile duct proliferation is a key feature of the tissue reaction to clinical and experimental forms of liver injury.
Extensive bile duct proliferation is a key feature of the tissue reaction to clinical and experimental forms of liver injury and in many cases, this proliferation may affect liver function [ 1, 2].
There was marked architectural distortion of lobular structure and extensive bile duct proliferation infiltrating into hepatocytes with periportal fibrogenesis and occasional fibrogenesis in the parenchymal area, suggesting activation of HSCs.
In these experiments, mammary primordia from E12.5 onwards formed extensive arborised ducts and have been used to evaluate postnatal mammary phenotypes in mice with genetic mutations which exhibit embryonic lethal phenotypes [ 3].
Extensive use of duct tape on slippers and items around the house brings this adage to life: Use it up, wear it out; make do or do without.
HGF on its own induces extensive formation of duct-like tubular structures (see Fig. 2b), whereas R5020 on its own produces cyst-like structures containing a single lumen (see Fig. 3c).
Normal human cells were quickly lost after intraductal injection, but cells infected with lentiviruses expressing CCND1, MYC, TERT, BMI1 and a short-hairpin RNA targeting TP53 were able to engraft and progressively replace the luminal layer in the mouse mammary ducts, resulting in the formation of an extensive network of humanized ducts.
Finally, the definitive kidney or metanephros is formed when the ureteric bud, an outgrowth of the distal nephric duct, undergoes extensive branching and induces the surrounding mesoderm to form glomeruli and nephrons [7], [8].
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