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Of the genes with biased expression in petal tissue, approximately 76% of homoeolog expression biases were immediately apparent after genomic merger, while the remaining 24% of homoeolog expression biases had been molded by evolutionary forces over time [ 20].

These findings indicate that upon allopolyploid formation, homoeolog expression biases happen in two, distinct temporal phases.

Specifically, expression biases reflective of cell proliferation were frequently identified on chromosome 6p21-23.

Regional expression biases (REBs) are genetic intervals where gene expression is coordinately changed.

Multiple regional areas of cytogenetic alterations and corresponding expression biases differentiating the two entities were identified.

However, expression biases were not evident when NRSE sequences were added to UAS-based reporter transgenes.

An additional directional trend in the data is a tendency for the allopolyploid genes to exhibit more extreme expression biases.

Perhaps, these exceptional gene expression biases indicated an additional level of gene expression regulation such as DNA methylation.

However, the utility of these approaches for genome-wide scanning of expression biases is not well described.

Further, we propose guidelines and a double selection strategy for minimizing the expression biases, without loss of information.

We demonstrated that chromosomal gene expression biases might correlate with chromosomal abnormalities found in chromophobe RCCs and ROs.

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