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Additionally, expression discrepancies between calcium channels may indicate potential sites of alternative transcription in a tissue-specific manner.
The possibility that the expression discrepancies in the background of ∆ oxyR between oxic and anoxic conditions were DMSO dependent can be excluded.
Other gene expression discrepancies may also be due to cell proliferation and recruitment in bronchial mucosa as part of the pathogenesis of asthma.
Not only does our array estimate homologous, but we can also detect expression discrepancies between two different samples; i.e., the squid head and body.
Although wide expression discrepancies had been found among these patient samples and cell lines, individual heterogeneity and the complexity of clinical samples (including different tumor stage, tumor size, patient age and gender, and etc).
The goal of this study was to identify a subset of genes involved in the color of the nacreous layer of the pearl oyster Pinctada margaritifera, and assess their expression discrepancies.
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The facts that Securin expression affects Separase mutation-mediated defects, and the existence of gender-specific Securin expression discrepancy, suggested that, the sexually dimorphic effects of Separase de-regulation on PGCs may be correlated with the gender-specific Securin expression.
Three reasons may help to explain this expression discrepancy.
To ascertain that the identified lncRNA is deregulated in the tongue SCC, we carried out real-time quantitative PCR to validate the expression discrepancy between the epithelial cancers and normal epithelia of the same patients.
Extracting and amplifying mRNA from cells obtained through the laser capture microdissection of the same formalin-fixed tissue that was used for immunohistochemistry might better clarify the mRNA/protein expression discrepancy observed in our study.
It is conceivable that identification of evident miRNA expression discrepancy among these samples with varying proportion of "good" and "bad" eggs is challenging, and such difficulties have also been documented in previous studies [ 25, 48].
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