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To solve this chicken-or-egg problem, Süel and his colleagues first set out to explore cell death in the biofilms.

Analysis of such mutations allows us to better understand the mutational processes in normal cells, explore cell lineages in development, and examine potential associations with age-related disease.

Here, we investigate crosslink-induced mechanotransduction of hPSCs cultivated on decellularized fibroblast-derived matrices (FDM) to explore cell adhesion, growth, migration, and pluripotency in various biological landscapes.

These developments are changing the way we explore cell communication and signal transduction, permitting deeper understanding of the physiological and pathophysiological processes.

ADSCs at density of 5 × 106 cells/mL were encapsulated into the gel-beads aiming to explore cell expansion under different conditions and the osteogenic induction of ADSCs was verified by specific staining.

Studies are underway to explore cell activation (i.e. microglial, astrocyte, neural), as well as global gene-expression profiles comparing control, LPS and isoflurane treatment groups to obtain a read out of the types of genes, including pro-inflammatory genes, channels, and pathways that may be sensitive to treatment.

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Furthermore, the revertant keratinocytes might offer the possibility to explore cell-based therapeutic strategies, by culturing in vitro and subsequently grafting as part of bioengineered dermo-epidermal substitutes on affected skin.

Such advances are required to explore cell-to-cell metabolic variations, as well as cells at different stages of the cell cycle.

Biological specimens collected during the study may also be used for further disease-related testing, including molecular typing to describe and compare selected biomarkers in AECOPD and stable COPD, to explore cell-mediated immune response to specific bacterial antigens, and to develop non-invasive bacterial diagnostic methods.

A number of methods for statistical deconvolution of mixed tissue gene expression data have been developed, which should be used to further explore cell-type specific expression in neurodegeneration once further human brain cell-specific gene expression profiles have been established [ 124].

In addition, air-dried detached leaves showed little variation in residual cellular water levels (between 58 62%) making it the preferred choice for inducing dehydration stress in experiments exploring cell responses in four different backgrounds and under different conditions as described here.

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