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Using hepatocytes as an experimental system, his lab explores cell lineage conversion with particular focus on inducing non-hepatic cells to form functional hepatocyte-like cells.
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To solve this chicken-or-egg problem, Süel and his colleagues first set out to explore cell death in the biofilms.
Analysis of such mutations allows us to better understand the mutational processes in normal cells, explore cell lineages in development, and examine potential associations with age-related disease.
Here, we investigate crosslink-induced mechanotransduction of hPSCs cultivated on decellularized fibroblast-derived matrices (FDM) to explore cell adhesion, growth, migration, and pluripotency in various biological landscapes.
These developments are changing the way we explore cell communication and signal transduction, permitting deeper understanding of the physiological and pathophysiological processes.
ADSCs at density of 5 × 106 cells/mL were encapsulated into the gel-beads aiming to explore cell expansion under different conditions and the osteogenic induction of ADSCs was verified by specific staining.
"He indicated that he took them to answer some questions in own mind about how difficult the terrain was to navigate and to explore cell reception issues," Thompson said.
Our aim was to clonally label cells in the mouse embryo to explore cell lineage restriction in the mammalian hindbrain.
To further explore cell spreading as a function of pH, we quantified membrane dynamics via kymography [40].
Here we explore cell movement by analyzing the direction, size and timing of ∼2000 pseudopodia that are extended by Dictyostelium cells.
Sophisticated experimental tools with high-resolution analysis have allowed us to explore cell lineage restriction within the hindbrain in mouse embryos.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com