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Factors that affect the process of calcium carbonate accretion in structural corals, such as Pocillopora and Acropora, have downstream influence on the habitat and food supply of other marine organisms [20].
Despite the unexpected direction of this response, it nevertheless provides a means for this downstream influence observed in response to miR-181b modulation.
While there is likely to be other miR-181b target genes with the potential to exert a downstream influence, these should be limited by the relatively short time frame of this experiment (24 hours).
Here, we show that distinct firing patterns of excitatory neurons in the central thalamus drive these opposing EEG rhythms, lead to dramatic differences in the spatial extent of forebrain recruitment, and switch the region's downstream influence on cortex from excitation to inhibition.
Similar(56)
Furthermore, volatile induction is known to be mediated by JA [ 34, 35] and thus is likely to reflect downstream influences of the JA induction we documented previously.
Although, it is impossible to entirely rule out reverse causation and confounding to obtain a truly exogenous measure of wealth in early life and estimate causal relationships, we were able to assess the downstream influences of an early life exposure on later life outcomes by using longitudinal data from Young Lives.
Elucidation of the molecular mechanisms by which Notch signaling and its downstream effectors influence tumorigenesis will facilitate therapeutic intervention of T cell leukemia and lymphoma and also shed light on the oncogenic effect of Notch on other cell types.
SIRT1 has been shown to deacetylate transcription factors and coactivators, whose downstream targets influence aggregate formation.
Finally, we have included genes that encode proteins capable of exerting indirect downstream regulatory influence (e.g. immune effectors).
Second, verification through the manipulation of auxin effectors is also not foolproof, as there is evidence that the downstream factors influence transport and hence the distribution of the upstream gradient that controls their expression [ 56].
By incorporating phylogenetic footprinting, the method reported in this study emphasizes SNPs present in genomic regions that are highly conserved between human and mouse, thereby increasing the probability of a downstream functional influence of variations within theses sequences.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com