Synchronization of estrus and ovulation can be enhanced by administration of EB or GnRH during proestrus, but dose, timing and stage of follicular development at the time of treatment can affect outcomes.
"Future research should explore the role of dose, timing, and route of triclosan exposure," the paper's authors wrote.
Pharmacology: data on drug-drug interactions, pharmacokinetics, pharmacodynamics, dosing or dose timing.
Comprehensive intervention protocols are described in terms of dose, timing, specific activities, modalities, and related outcomes.
In designing vaccine regimens, one must consider further dose, timing of doses, adjuvants, and routes of vaccination.
The very structure of clinical trials may be contributing to this because assumptions made during trial planning preclude additional learning within residual important areas of uncertainty, such as dose, timing, and duration of treatment.
Clinicians should consult the ASRA guidelines for recommendations on total daily dose, timing of the first postoperative dose, and dose schedule for anticoagulants used in conjunction with RA/PRA.
Aspects such as the dose, timing and intensification of anti-tumour necrosis factor therapy affect the likelihood of achieving deep remission, but definitive evidence on long-term benefits and the risk/benefit profile of treatment intensification is needed.
Although our results did not demonstrate a significant effect of structured group reminiscence therapy on overall behavior competency or on physical functioning in elders with dementia, we identified issues related to future implementation of this intervention, such as study power, chosen outcome measures, intervention dose, timing of outcome measures, or cultural applicability issues.
Melatonin supplements may help -- but dose timing is critical.
The present study reports three further experiments where we investigate the effects of DNA dose, timing, and formulation.
