The elements of interest (Ca, Mg) were assayed using different timing parameters, namely the irradiation time (t i), the decay time (t d) and the counting time (t c).
In addition, the radiosensitization efficacy was dependent on the timing of irradiation.
Our purpose was to explore the risks of irradiation regarding dose levels, timing of radiation, implant location, and material.
The timing of irradiation, post- versus pre-operatively, does not seem to influence local control rates.
For the timing of irradiation, we can present some systematic data obtained with high-dose rate (2 Gy in 2 min) shifted through the culture time.
As the timing of irradiation relative to drug application may play an important role in combined modality treatments, tumour cells were irradiated at different time intervals between 24 h pemetrexed treatment and irradiation.
The differences between the protocol used here and the usual procedure relate to culture time (4 instead of 3 days) and to the timing of the irradiation.
The full width half maximum (FWHM) timing jitter before irradiation was ≈600 ps for SLiK, ≈550 ps for C30921SH, and ≈700 ps for SAP500S2.
However, essential questions relating to the optimisation of thoracic radiotherapy remain unanswered, including volume of irradiation, optimal total dose, fractionation, timing and sequencing of radiation.
The extent of lung-colony inhibition was shown to depend on both the dose and timing of abdominal irradiation.
