Rapid cooling causes transient increases in discharge frequency, whereas rapid warming produces transient discharge inhibition.
In fact, mechanoreceptor nerve fibres that are sensitive to cold have increased spontaneous discharge frequency in the presence of cold stimuli.
When the receptor is rapidly cooled, its discharge frequency rises steeply and then declines gradually to a lower constant level; on rapid warming, the opposite response occurs.
If the cooler temperature is maintained, the discharge frequency adapts to a frequency of static discharge that is directly related to the cooler temperature.
Cold receptors respond to sudden cooling with a transient increase in discharge frequency (called the dynamic response) that is directly related to the prior temperature and the magnitude and rate of the temperature decrease.
When the cold receptor is warmed again, a transient decrease, or inhibition, in discharge frequency occurs, after which the frequency rises again and finally adapts to a new static value.
Warm receptors respond in a similar fashion to that of cold receptors, except that they show a dynamic response of increased discharge frequency to warming and a transient inhibition of discharge to cooling.
The results indicate that discharge frequency has a negligible influence on the conversion of CO2 at a constant discharge power.
Increasing pulse-off time decreases the effective discharge frequency and hence decreases the discharge energy across the electrodes resulting in low machining rate.
Furthermore, CGRP may modulate central sensitization by increasing the discharge frequency of wide dynamic range neurons in the spinal cord, thus modulating nociceptive transmission [27].
By adjusting discharge frequency and duty cycle, the cluster mass can be decreased by one order of magnitude.
