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They inhibit gene expression largely in a post-transcriptional manner, by recognizing a specific complementary sequence usually located in the 3′ UTR of a target mRNA.

Emerging highly selective compounds for anticancer therapy are oligonucleotide aptamers that interact with their targets by recognizing a specific three-dimensional structure.

SOX9 functions as a transcription factor by recognizing a specific heptameric DNA sequence (A/T)(A/T CAA(A/T G through its high mobility group (HMG -box domain.

It is conceivable that the CHHC Zn-finger domain may mediate this selective binding by recognizing a specific shape or particular structure of the cognate tRNAs.

The A domain functions by recognizing a specific amino or hydroxyl acid substrate and activating it as aminoacyl adenylate via ATP hydrolysis.

The HEG within the ω intron has been documented to promote intron insertion by recognizing a specific 18-nucleotide exon sequence (5′-TAGGGATAACAGGGTAAT-3′) (Dujon 1989).

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Similar(53)

The Neisseria sp. and members of the Pasteurellaceae, such as H. influenzae, discriminate between homologous and alien DNA by recognizing a short specific sequence in DNA from their own genus.

It was observed that emotion recognition was allowed by the development and the generalization of an emotional script, that is, a child can recognize a specific emotion by verifying the presence of several prototypical elements that are arranged in precise causal and temporal sequences.

Radeke and colleagues have demonstrated that CD4+ T cells alone were sufficient as initiators and effectors in nephritis, by recognizing specific antigens expressed within the glomeruli in an experimental mouse model of GN [ 21].

Toll-like receptors (TLRs) play a crucial role in innate immunity by recognizing specific pathogen-associated molecular patterns including lipoproteins, lipopeptides, lipopolysaccharide, flagellin, dsRNA, ssRNA and CpG DNA motifs (Akira and Takeda 2004; West et al. 2006).

RpoN (σ54 or sigma 54) is a subunit of the RNA polymerase and plays a critical role in the regulation of gene expression by recognizing specific promoter elements and initiating transcription.

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