Sentence examples for by establishing a specific from inspiring English sources

An active catalytic core for XBP1/HAC1 mRNA cleavage is unlikely to consist of all subunits within the IRE1 oligomer, but rather, oligomerization will lead to formation of the catalytically active pocket by establishing a specific orientation of catalytic residues.

Altogether, these observations indicate that AS plays a major role in EMT by establishing a specific program of splice variants of genes important for epithelial and mesenchymal cell morphology and motility.

This study confirms the potential for human iPSC to model inherited arrhythmogenic syndromes by establishing a patient-specific model of CPVT in which to test therapeutic interventions that have been successful in our murine model of CPVT.

Precise clinical characterization will be refined by establishing a concomitant ARPKD specific biobank and reference histology.

And while tourism cannot solve the problem of rising sea temperatures, the industry's cooperation to eliminate specific pressures — by establishing a well-enforced no-take zone, or reducing wastewater pollution, for example — helps reefs recover from bleaching and disease.

In this study we attempt to fill this gap by establishing a general picture upon which more specific and context-dependent situations can be studied and understood.

Thus, the sweep in this region may reflect strong recent selection by breeders to establish a specific Brahman ear morphology type.

In my opinion, the manuscript fully deserves to be published by eLife because it solidly establishes a specific role of ribosome protein uS7 in initiation process.

Our study further qualifies these findings by establishing that specific microbial composition, rather than the microbiota as such, influences Type 1 IFN signalling during early colonization and development.

The objective of this study was to develop robust xenograft models by establishing the specific experimental conditions (cell dose, dissemination tropism, growth kinetics, symptoms, lethality and stability of cell surface markers) required for the evaluation of therapeutic agents in routine and easy-to-use setting.

Spence's work convinced him that discrimination learning takes place by establishing connections between specific stimuli and responses, reinforced by a reward when the proper response is given.