Sentence examples for by early activation of from inspiring English sources

This study tested the hypothesis that the cellular response in the kidney to sepsis is characterized by early activation of AMP activated protein kinase (AMPK), and that such activation is temporally associated with downregulation of the epithelial sodium channel (B-ENaC).

Central precocious puberty (CPP) is a common pediatric endocrine disease caused by early activation of hypothalamic-putuitary-gonadal (HPG) axis, yet the exact mechanism was poorly understood.

CPP is widely accepted as an endocrine disorder caused by early activation of HPG axis which belongs to the neuro-endocrine-immune (NEI) system.

A direct analysis of coagulation factors in SAH patients is hampered by early activation of the coagulation and fibrinolytic system following the hemorrhage [ 21].

The acute response to sepsis was characterized by early activation of AMPK which increased from 6 to 18 hours, peaked at 24 hours, and decreased by 48 hours.

As shown in Fig.  6, gp120 triggers a cascade of signaling events initiated by early activation of STAT3 leading to IL-6 production.

The poor functional recovery observed in G93A-SOD1 tranimalsc animals was accompanied by the induction of fewer pro-survival signals, by an early activation of inflammatory markers, of several pro-apoptotic genes involved in cytochrome-C release and by the persistent up-regulation of the heavy neurofilament subunits and of genes involved in membrane excitability.

Neuroinflammation following TBI is mediated by an early activation of the innate immune system [ 5].

It is suggested that cultured tissues respond to in vitro conditions by an early activation of defense mechanisms already noticed after 24 h of culture.

This might be explained by an early activation of glycogenolysis in the major glucose storing tissues (i.e. muscle and liver [ 21]).

For instance, A-928605 produced significant changes both by inhibiting early activation of molecules within the IGF signaling pathway and translationally that can be directly attributed to inhibition of IGF1R because none of these effects occurred in the vector control line.