Sentence examples for by precocious activation of from inspiring English sources
Interestingly, oogenesis is impaired in chimeric ovaries lacking autophagy in a subset of follicle cells but not in the germline, which may be caused at least in part by precocious activation of Notch signaling in mutant follicle cells [ 127, 129].
Our present findings indicate that ATR/Mec1 acts through the replication checkpoint to prevent chromosome rearrangements and to modulate DDT outcome by counteracting the precocious activation of a cell cycle, mitotic CDK1-driven recombination pathway prone to crossover formation.
Gα2-null mutants do not aggregate and overexpression of wild-type Gα2 results in precocious activation of guanylyl cyclase by cAMP in vegetative cells [ 14].
In addition, we also observed a delay in the precocious activation of ISC proliferation, as measured by phosphorylation of histone H3 (pHH3), a marker of cell cycle progression through mitosis.
Similar defects were also found in egg chambers lacking autophagy, and mutations in Atg1 or Atg13 were found to induce precocious activation of the Notch pathway as shown by the expression of the Notch downstream effectors Cut and Hindsight (Hnt) [ 59].
However, Hr46 overexpression induced a precocious activation of CG15545-GFP reporter expression.
The loss of both Cav-1 alleles results in precocious MG development during pregnancy and the concomitant precocious activation of STAT5.
Mutations in skr-5 also block the precocious activation of the UPS and the increased longevity observed in let-23 sa62 let-23 sa62
Whether this reflects an increase in the number of Pros-expressing cells in the embryo or precocious activation of Pros remains to be determined.
Moreover, forced expression of miR-195 in heart was sufficient to cause cardiomyocyte loss leading to HF, and precocious activation of miR-195 in the heart suppressed the neonatal regeneration capacity of the murine heart [ 64].
The evolutionary loss of accessory cells in the BO is therefore simply explained by precocious abrogation of ommatidial differentiation (Fig. 8).
