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Exact(5)
It should be noted that ATF4 deficiency did not completely block the anabolic actions of PTH since this hormone increased bone volume in both growing and adult OVX bones from Atf4−/− mice (Figs. 1 3).
Reconstructions of the trabecular bone in distal femurs illustrated the striking reduction in bone volume in both CKO and CKOOsx mice as compared to their wildtype and heterozygous littermates (Figure 4A).
This suggested that combination therapy had clear benefit on tumor burden and bone volume in both intact (androgen positive) and castrated (androgen negative) mice models of PC.
In contrast, estradiol is also directly bone anabolic, explaining the increase in bone volume in both OVX+E+Sal and OVX+E+IA groups (compare with Figures 5b, d and 5f).
Bone morphometric and histological analyses on 4-week-old Sf as well as wild type (WT) littermates show significant reduction of bone volume in both trabecular and cortical bones of Sf mice.
Similar(55)
Upon implantation in mouse calvarial defects, both the immobilized ALP/FS and FS alone treated group had higher bone volume in the defect compared to the empty defect control.
Histomorphometric analyses revealed that hypergravity suppressed both bone formation and resorption and increased bone volume in ovariectomized rats.
Histology revealed presence of synovial hyperplasia in both mBSA-injected groups, but mBSA-injected wt mice had decreased trabecular bone volume in distal femoral metaphyses (BV/TV) compared to controls (1.08 ± 0.57 vs. 2.55 ± 0.43; p < 0.05, t-test).
Histomorphometry identified a significant increase in bone volume in the BMA group compared to JAX™ alone.
To reconstruct adequate bone volume in alveolar bone width deficient area, three-dimensional bone overfilling is required since bone graft materials undergo gradual resorption in both width and height.
Fractional bone volume in rats treated with PTH(1 34) increased significantly in all groups compared to that of vehicle treatment.
Related(20)
blood volume in both
marrow volume in both
bone quantity in both
bone levels in both
bone shape in both
bone metabolism in both
bone ingrowth in both
bone development in both
bone erosion in both
bone homeostasis in both
bone marrow in both
bone microenvironment in both
bone matrix in both
bone microstructure in both
bone resorption in both
bone turnover in both
bone defect in both
bone health in both
bone void in both
bone length in both
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