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In addition, ethylene, auxin and jasmonic acid hormones were more related to DXR-mediating light response, suggesting candidate genes involved in the DXR-mediating cross-talk between light response and hormone regulation.

Recently, a connection between light response and carbon source signaling was discovered.

Besides the intriguing insights into fungal physiology, these findings also provide perspectives for research towards elucidation of the interplay between light response and metabolism in higher organisms.

Although our study was focused on elucidation of the interrelationship between light response and nutrient signaling, the fact that sexual development of T. reesei is dependent on light [ 28] draws a logical connection of these signaling pathways to sexual development.

In summary, all three photoreceptors of N. crassa execute distinct roles in regulation of cellulase utilization and are hence crucial determinants of the interconnection between light response and carbon metabolism.

The photoreceptor-orthologs BLR1 and BLR2 are known to mediate almost all known light responses in these fungi and another light-regulatory protein, ENVOY, is suggested to establish the connection between light response and nutrient signaling.

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The enrichment of the GO categories "mitochondrial envelope" and "mitochondrial part" from the cellular component field (Figure S2 and Table S3) and of "mitochondrial diseases" in the MeSH analysis (Table S8) lends further support to a link between the light response and mitochondrial function.

Therefore, even though the benefit is presumably small, a link between the pupillary light response and visual attention is beneficial.

We highlight the link between the pupillary light response and eye-movement preparation: When you intend to look at a bright stimulus, a pupillary constriction is prepared along with the eye movement before the eyes set in motion.

The time to peak was defined as the time between the beginning of the light response and its maximum amplitude (i.e. the most negative value of the membrane potential); the response amplitude was the difference between the resting membrane potential and the membrane potential at the peak response; and the duration of the response was the duration of the hyperpolarization.

For example, Genoud et al. reported interactions between phytochrome-mediated light responses and SA-triggered responses in Arabidopsis [ 12].

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