Ai Feedback
Exact(7)
While a positive correlation between objective response and survival was observed in our cohort, genome-wide analysis showed no significant differences in the overall mutation load (Supplementary Fig. 3) or neoantigen load (Supplementary Figs. 4 and 5) over time or between responders and non-responders, consistent with previously observed weak associations8, 14.
We found a marked double dissociation between objective response and subjective confidence: instances in which subjects systematically responded correctly at very low confidence and others in which subjects responded systematically incorrectly with very high confidence in their response.
Figure 3 shows the results of correlation between objective response and TATO in 36 patients.
The intervals between objective response and local recurrence were less than 12 months in 5 patients (range, 2.6 to 9.7 months).
There was no relationship between objective response and weight loss for patients with either SCLC (P=0.3) or NSCLC (P=0.5) (Table 4 >).
A meta-analysis of metastatic breast cancer studies found a positive relationship between objective response and overall survival on an individual patient basis, but the relationship was less clear when treatment regimens were compared (Bruzzi et al, 2005).
Similar(53)
A similar association between objective responses and ethnicity was observed in studies on erlotinib monotherapy for previously treated advanced NSCLC.
There was no significant association between objective response rate and the angiogenesis-related proteins investigated.> There was a trend toward an association between better PFS with lower NOTCH1 expression (p = 0.06, Fig. 4a).
The subsequent analysis of large clinical trials has demonstrated a clear negative relationship between objective response rates and the occurrence of mutations in the KRAS gene, establishing KRAS mutations as negative predictors for EGFR-targeted therapies in mCRC (Amado et al, 2008; Karapetis et al, 2008; Lievre et al, 2008).
Based on the FEM results, RSM is used to establish a response model to depict the function relationship between the objective response and design variables.
This was consistent with the imprecise correlation between the objective response and the survival outcome [ 42].
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com