Sentence examples for base mismatch from inspiring English sources

We report on a simple approach to enhance solid-phase hybridization-based single base mismatch discrimination at high ionic strength based on the deliberate insertion of a natural DNA base mismatch in the surface-tethered probe.

It shows excellent selectivity against non complementary sequences and 3 base mismatch complementary targets.

Their results showed that the detection of the perfect match sequence was 2.5 times higher than the single base mismatch and the fluorescence enhancement response of the three-base mismatch was only 15% that of the perfect complementary DNA target.

The suggested biosensors were applied for determination of DNA sequences and showed excellent selectivity for discriminating the complementary sequences from various targets such as non-complementary, one base-mismatch and three base mismatch sequences.

Selectivity of designed electrode was ascertained by response signal for complementary, non-complementary and 1 base mismatch sequences.

Capture probe with single base mismatch was prepared to detect the specificity and sensitivity of hybridization on microarray.

A 5-base mismatch tMO1 was designed (5' -CTTTgGGACcGTCcGTgGTgTTTA-3'), the mismatched bases were indicated by subscripts.

The Qdot-based MB was used to detect perfect match, single-base mismatch and three-base mismatch DNA sequences.

Both perfect complementary and single-base mismatch were detected.

In addition, we presented an easy and inexpensive way for single-base mismatch detection.

This method also shows single-base mismatch discrimination capability as well.