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Justyna Jupowicz-Kozak

CEO of Professional Science Editing for Scientists @ prosciediting.com

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are mediated by

Grammar usage guide and real-world examples

USAGE SUMMARY

The phrase "are mediated by" is correct and usable in written English.
It can be used to describe a process where something is facilitated or influenced by an intermediary or a specific factor. Example: "The effects of climate change on agriculture are mediated by various environmental factors, including temperature and precipitation."

✓ Grammatically correct

Science

News & Media

Academia

Human-verified examples from authoritative sources

Exact Expressions

60 human-written examples

Secondly, anti-tumor effects are mediated by Fc-mediated ADCC.

"And newspapers are mediated by editors.

News & Media

The New York Times

These effects are mediated by the GAP domain of PlexinD1.

Science & Research

Nature

Rather, the effects are mediated by glucose.

The effects of the Wnts are mediated by Frizzled receptors.

Our attempts to make use of these vast stores of information are mediated by search algorithms.

Key interactions in this network are mediated by PDZ domains.

Science

Structure

Its biological effects are mediated by four receptor types.

Some of these influences are mediated by epigenetic mechanisms.

Both responses are mediated by a single pathway of interneurons.

Indeed, most of the actions of pituitary growth hormone are mediated by IGFs, primarily IGF-1.

Encyclopedias

Britannica
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Expert writing Tips

Best practice

When using "are mediated by", ensure clarity about the specific mechanism or agent that is facilitating the process. Vague references can weaken the sentence's impact.

Common error

While grammatically correct, excessive use of passive voice, including phrases like "are mediated by", can make writing sound convoluted. Consider rephrasing sentences in the active voice for more direct and engaging prose.

Antonio Rotolo, PhD - Digital Humanist | Computational Linguist | CEO @Ludwig.guru

Antonio Rotolo, PhD

Digital Humanist | Computational Linguist | CEO @Ludwig.guru

Source & Trust

84%

Authority and reliability

4.5/5

Expert rating

Real-world application tested

Linguistic Context

The phrase "are mediated by" functions as a passive construction, indicating that a particular action or effect is brought about or influenced by an intervening factor or mechanism. Ludwig AI shows numerous examples of its usage across diverse fields.

Expression frequency: Very common

Frequent in

Science

60%

Academia

20%

News & Media

10%

Less common in

Encyclopedias

5%

Formal & Business

3%

Wiki

2%

Ludwig's WRAP-UP

In summary, "are mediated by" is a grammatically sound and frequently used phrase to express that a process or outcome is influenced or facilitated by a specific mechanism or agent. As Ludwig AI highlights, it's prevalent in scientific, academic, and news contexts, denoting a formal and precise register. While correct, overuse can lead to passive and convoluted writing, making alternatives like "influenced by" or "caused by" preferable in some instances. When clarity about the specific mechanism is crucial, "are mediated by" remains the most appropriate choice.

FAQs

How can I rephrase "are mediated by" to sound more active?

Consider using alternatives such as "influence", "affect", or "facilitate". For example, instead of "The effects are mediated by glucose", you could say "Glucose influences the effects".

What is the difference between "are mediated by" and "are caused by"?

"Are caused by" indicates a direct cause-and-effect relationship. "Are mediated by" suggests an intermediary factor that influences or facilitates the relationship, making it less direct.

When is it best to use "are mediated by" in scientific writing?

Use "are mediated by" when you want to emphasize the specific mechanisms or pathways through which an effect occurs. This is particularly useful when describing complex biological or chemical processes.

Are there situations where "are influenced by" is a better choice than "are mediated by"?

Yes, if you want to broadly indicate an effect without specifying the exact mechanism. "Are influenced by" is less specific and can be used when the mediating factors are not fully understood or when you want to avoid technical jargon.

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Authority and reliability

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Real-world application tested

Most frequent sentences: