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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com
are mediated by
Grammar usage guide and real-world examplesUSAGE SUMMARY
The phrase "are mediated by" is correct and usable in written English.
It can be used to describe a process where something is facilitated or influenced by an intermediary or a specific factor. Example: "The effects of climate change on agriculture are mediated by various environmental factors, including temperature and precipitation."
✓ Grammatically correct
Science
News & Media
Academia
Alternative expressions(20)
are caused by
are influenced by
are affected by
are driven by
are facilitated by
are determined by
are governed by
stem from
result from
are channeled through
are associated by
are initiated by
are attributed by
are ascertained by
are activated by
are dictated by
are associated via
are related through
are reliant on
are dependent on
Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Human-verified examples from authoritative sources
Exact Expressions
60 human-written examples
Secondly, anti-tumor effects are mediated by Fc-mediated ADCC.
Science
"And newspapers are mediated by editors.
News & Media
These effects are mediated by the GAP domain of PlexinD1.
Science & Research
Rather, the effects are mediated by glucose.
Science
The effects of the Wnts are mediated by Frizzled receptors.
Our attempts to make use of these vast stores of information are mediated by search algorithms.
News & Media
Key interactions in this network are mediated by PDZ domains.
Science
Its biological effects are mediated by four receptor types.
Some of these influences are mediated by epigenetic mechanisms.
Science
Both responses are mediated by a single pathway of interneurons.
Science
Indeed, most of the actions of pituitary growth hormone are mediated by IGFs, primarily IGF-1.
Encyclopedias
Expert writing Tips
Best practice
When using "are mediated by", ensure clarity about the specific mechanism or agent that is facilitating the process. Vague references can weaken the sentence's impact.
Common error
While grammatically correct, excessive use of passive voice, including phrases like "are mediated by", can make writing sound convoluted. Consider rephrasing sentences in the active voice for more direct and engaging prose.
Source & Trust
84%
Authority and reliability
4.5/5
Expert rating
Real-world application tested
Linguistic Context
The phrase "are mediated by" functions as a passive construction, indicating that a particular action or effect is brought about or influenced by an intervening factor or mechanism. Ludwig AI shows numerous examples of its usage across diverse fields.
Frequent in
Science
60%
Academia
20%
News & Media
10%
Less common in
Encyclopedias
5%
Formal & Business
3%
Wiki
2%
Ludwig's WRAP-UP
In summary, "are mediated by" is a grammatically sound and frequently used phrase to express that a process or outcome is influenced or facilitated by a specific mechanism or agent. As Ludwig AI highlights, it's prevalent in scientific, academic, and news contexts, denoting a formal and precise register. While correct, overuse can lead to passive and convoluted writing, making alternatives like "influenced by" or "caused by" preferable in some instances. When clarity about the specific mechanism is crucial, "are mediated by" remains the most appropriate choice.
More alternative expressions(10)
Phrases that express similar concepts, ordered by semantic similarity:
are influenced by
Focuses on the general impact or effect rather than the specific mechanism of mediation.
are affected by
Emphasizes the resultant change or alteration due to an external factor.
are caused by
Highlights the direct causal relationship between two elements.
are driven by
Suggests a strong force or motivation behind the action or process.
are facilitated by
Indicates that something is made easier or possible by a particular element.
are determined by
Stresses the definitive role of a factor in setting a specific outcome.
are governed by
Implies a rule-based or regulatory influence on the process.
stem from
Highlights the origin or source from which something arises.
result from
Focuses on the outcome or consequence of a specific cause.
are channeled through
Suggests a specific pathway or mechanism by which something is directed or conveyed.
FAQs
How can I rephrase "are mediated by" to sound more active?
Consider using alternatives such as "influence", "affect", or "facilitate". For example, instead of "The effects are mediated by glucose", you could say "Glucose influences the effects".
What is the difference between "are mediated by" and "are caused by"?
"Are caused by" indicates a direct cause-and-effect relationship. "Are mediated by" suggests an intermediary factor that influences or facilitates the relationship, making it less direct.
When is it best to use "are mediated by" in scientific writing?
Use "are mediated by" when you want to emphasize the specific mechanisms or pathways through which an effect occurs. This is particularly useful when describing complex biological or chemical processes.
Are there situations where "are influenced by" is a better choice than "are mediated by"?
Yes, if you want to broadly indicate an effect without specifying the exact mechanism. "Are influenced by" is less specific and can be used when the mediating factors are not fully understood or when you want to avoid technical jargon.
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Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Source & Trust
84%
Authority and reliability
4.5/5
Expert rating
Real-world application tested