Lost expression of tumour-suppressor-miRs leads to accelerated cell growth, cell cycle progression, and impaired inhibition of oncogenes gene expression (Fig. 4).
But even this didn't give her as big a thrill as the lost expression on Milena's face.
"Their faces kind of lost expression because I think they seen — you could see it.
I can't take my eyes away from his glazed, lost expression, his eyes, as big as saucers, staring blankly back at my camera.
We also showed that DNA methylation may underlie the lost expression of MEG3 in NSCLC tissues.
Furthermore HCC1428-LTED lost expression of both CXCL11 and CXCL12, a feature associated with chemotactic response to ligand gradients and not associated with proliferation [ 30].
All PGAs in LS patients were MSI-high and lost expression of mismatch-repair proteins (MLH1/PMS2 in 2 cases and MSH2/MSH6 in 1 case), whereas none of the 14 sporadic PGAs was MSI-high or had lost expression of mismatch-repair proteins.
Sections without nuclear staining in the tumor cells, in the presence of normal nuclear staining in lymphocytes and normal epithelial or stromal cells in the same section, were considered to have a lost expression (Fig. 1).
Our current study also found that lost expression of miR-339-5p miR-339-5p miR-339-5preast cancer metastasis to lymph nodes, higher clinical stages, poor overall survival, and poor relapse-free survival of breast cancer patients.
Monocytes differentiated in vitro in the presence of IL-4 and GM-CSF lost expression of their homing markers and failed to express those found on normal circulating DC, rendering MoDC with a homeless phenotype.
