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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com
with significant difficulty
Grammar usage guide and real-world examplesUSAGE SUMMARY
The phrase "with significant difficulty" is correct and usable in written English.
It can be used to describe a situation where something is accomplished, but only after facing considerable challenges or obstacles. Example: "She managed to complete the marathon with significant difficulty, pushing through the pain and exhaustion."
✓ Grammatically correct
Science
News & Media
Alternative expressions(20)
with great struggle
with considerable effort
with considerable difficulty
with great effort
with much struggle
against all odds
laboriously
through sheer determination
with immense difficulty
with painstaking care
with utmost effort
with considerable exertion
with substantial effort
with great determination
with great intensity
with great difficulty
with greater effort
with enormous effort
with tremendous effort
with hard work
Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Human-verified examples from authoritative sources
Exact Expressions
4 human-written examples
The child was able to grasp objects and bring both hands to the midline, but with significant difficulty.
Science
The trial was as inclusive as possible, but patients requiring urgent assessment, private patients and patients with significant difficulty communicating in English were excluded.
Science
At the 15-year follow-up, 43 (83%) patients could squat normally, 7 (13%) others could do it with slight difficulty and 2 patients (4%) could squat with significant difficulty.
Although in some previous in vitro studies [ 9, 28], the skin was stretched more largely, we selected the stretching amount of 23% because stretching of in vivo forehead skin perpendicular to the body axis more than 23% was with significant difficulty.
Science
Human-verified similar examples from authoritative sources
Similar Expressions
56 human-written examples
The protein folding problem remains elusive, with significant difficulties still arising when modeling amino acid sequences lacking an identifiable template.
Science
The administration of local anesthetic before surgery to the great toe is often associated with significant difficulties, delaying surgery and increasing risk.
It is associated with significant difficulties with respect to monitoring.
Science
Patients with significant difficulties in language expression or comprehension were excluded, as were those meeting the exclusion criteria applied to the normal population.
People diagnosed with schizophrenia have significant difficulty accurately recognising emotions expressed by others.
Science
Studies concur in finding that females with XXX showed significant difficulties with arithmetic, with around 65% of females finding it difficult.
While these analogies are certainly noteworthy, there is a significant difficulty with the central claim.
Science
Expert writing Tips
Best practice
Use "with significant difficulty" when you want to convey that something was achieved but required substantial effort and faced notable obstacles. It adds more emphasis than simply saying something was "difficult".
Common error
Avoid using "with significant difficulty" repeatedly in close proximity. Vary your language to prevent the writing from becoming monotonous; consider using synonyms like "with great effort" or "after a hard time" instead.
Source & Trust
80%
Authority and reliability
4.1/5
Expert rating
Real-world application tested
Linguistic Context
The phrase "with significant difficulty" functions as an adverbial phrase, modifying a verb or verb phrase to describe the manner in which an action is performed. It indicates the degree of effort or challenge involved in the action, as shown by Ludwig's examples.
Frequent in
Science
50%
News & Media
50%
Formal & Business
0%
Less common in
Academia
0%
Encyclopedias
0%
Wiki
0%
Ludwig's WRAP-UP
In summary, "with significant difficulty" is a grammatically correct adverbial phrase used to describe an action performed with considerable effort and challenge. Ludwig's analysis reveals it's most frequently used in scientific and news contexts. Alternatives such as "with great effort" or "with much struggle" can provide variety. While grammatically sound, overuse should be avoided to maintain writing clarity and avoid monotony. Ludwig AI confirms the phrase's validity and provides numerous examples to illustrate its usage.
More alternative expressions(6)
Phrases that express similar concepts, ordered by semantic similarity:
with considerable difficulty
Replaces "significant" with "considerable", emphasizing the amount of difficulty.
with great effort
Focuses on the effort expended rather than the difficulty itself.
with much struggle
Highlights the struggle involved in completing the task.
against all odds
Emphasizes overcoming seemingly insurmountable obstacles.
despite substantial obstacles
Emphasizes the presence of obstacles that were overcome.
laboriously
Expresses doing something in a way that requires a lot of time and effort
arduously
Expresses doing something in a way that is very difficult
with notable hardship
Highlights the presence of a notable hardship.
after a hard time
Indicates the achievement followed a period of difficulty.
with a lot of trouble
Indicates the achievement followed a series of problems.
FAQs
How can I use "with significant difficulty" in a sentence?
You can use "with significant difficulty" to describe how someone performed an action. For example: "She managed to complete the marathon "with significant difficulty", pushing through the pain and exhaustion."
What are some alternatives to "with significant difficulty"?
Alternatives include phrases like "with considerable difficulty", "with great effort", or "with much struggle", depending on the specific nuance you wish to convey.
Is it better to say "with significant difficulty" or "with great difficulty"?
Both "with significant difficulty" and "with great difficulty" are grammatically correct and very similar in meaning. The choice between them often comes down to personal preference or stylistic considerations.
What's the difference between "with significant difficulty" and "with slight difficulty"?
"With significant difficulty" implies a considerable amount of effort and obstacles were involved, while "with slight difficulty" suggests only a minor challenge was present. The degree of effort is the key difference.
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Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Source & Trust
80%
Authority and reliability
4.1/5
Expert rating
Real-world application tested