Used and loved by millions
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com
was initially hypothesized to
Grammar usage guide and real-world examplesUSAGE SUMMARY
"was initially hypothesized to" is a grammatically correct phrase and can be used in written English.
Example: The new treatment was initially hypothesized to be effective, but further research showed inconsistent results.
✓ Grammatically correct
Science
Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Human-verified examples from authoritative sources
Exact Expressions
5 human-written examples
Caveolin-1 was initially hypothesized to be a tumor suppressor in breast cancer [ 13].
Science
Clonal expansion was initially hypothesized to be driven by a selective advantage for deleted mtDNA species over wild-type mtDNA molecules based upon replicative turnover (9).
Science
Combat-related stress was initially hypothesized to be one of the factors responsible for the illnesses afflicting Gulf War veterans [ 177]; as a result, it was one of the few factors surveyed by all of the studies.
Initial measures of serum noradrenaline verified an inverse relation between serum levels and mortality, which was initially hypothesized to be a hormonal marker of hemodynamic stress, and later with the appreciation of the value of beta blockers to improve morbidity and mortality in heart failure, felt to itself be a mediator of the increased mortality rates [ 47, 48].
The T-to-C substitution was initially hypothesized to create an Sp-1 binding site, which could lead to up-regulation of transcriptional activation of the variant allele and higher activity of the enzyme [ 8, 9], but this was not observed in experimental studies [ 10- 12].
Science
Human-verified similar examples from authoritative sources
Similar Expressions
55 human-written examples
Neighbors were initially hypothesized to be good key informants on the grounds of the close proximity of living quarters in camps for refugees and for internally displaced persons (IDPs) that generally are present in conflict-affected settings.
Science
These compounds were initially hypothesized to inhibit the enzymes through the previously described nucleophilic attack/elimination/Lössen rearrangement reported by Groutas et al. for the structurally similar succinamide inhibitors of elastase.
Science
This is contrary to what was initially hypothesized and what NGO reports and media stories would lead readers to believe.
Science
In contrast to what was initially hypothesized, the evolution of pathogenic bacteria, that are specialized bacteria of particular interest to humans [ 50], consists mainly of gene losses [ 10, 51, 52].
Science
Based on this information, it was initially hypothesized that dimorphism in cassava could be due to unreduced pollen grains.
Science
It was initially hypothesized that addition of FL treatment expression data to the training compendium could also minimize background gene-gene interactions specific to FL's effects.
Science
Expert writing Tips
Best practice
Use "was initially hypothesized to" when describing an early-stage hypothesis that has since been tested or revised. This emphasizes the evolution of understanding.
Common error
Avoid presenting information that "was initially hypothesized to" be true as current fact without providing updated evidence or acknowledging the shift in understanding. Always clarify whether the initial hypothesis was supported or refuted by subsequent research.
Source & Trust
83%
Authority and reliability
4.1/5
Expert rating
Real-world application tested
Linguistic Context
The phrase "was initially hypothesized to" functions as a reporting verb phrase. It introduces a hypothesis that was proposed at an earlier stage. This type of construction is common in scientific and academic writing to describe the evolution of understanding.
Frequent in
Science
80%
News & Media
10%
Formal & Business
10%
Less common in
Encyclopedias
0%
Wiki
0%
Reference
0%
Ludwig's WRAP-UP
In summary, "was initially hypothesized to" is a phrase used to introduce early-stage hypotheses, predominantly in scientific and academic writing. As Ludwig AI correctly points out, the phrase is grammatically sound and serves to contrast past assumptions with present knowledge. It is less common in informal contexts and should be used when precision and a formal tone are required. Remember to clarify whether the initial hypothesis was supported or refuted by subsequent research to avoid misleading your audience. Alternatives such as ""was originally theorized to"" or ""was first thought to be"" can be used depending on the context.
More alternative expressions(10)
Phrases that express similar concepts, ordered by semantic similarity:
was originally theorized to
Replaces "hypothesized" with "theorized", indicating a formal theory being initially considered.
was first thought to be
Uses "thought" to emphasize the initial belief or understanding before further investigation.
was at first assumed to
Highlights the initial assumption made about something, which may later be revised.
was preliminarily proposed to
Emphasizes the preliminary nature of the proposal, suggesting it's subject to change.
was tentatively suggested to
Indicates a suggestion made with caution and subject to further scrutiny.
was provisionally posited to
Highlights that the statement was used to explore implications based on current evidence or theory.
was speculatively considered to
Emphasizes the speculative aspect of the initial consideration, implying uncertainty.
was conjecturally proposed to
Indicates a proposal based on conjecture rather than solid evidence.
was tentatively put forward as
Similar to suggesting, but indicates a formal presentation of an idea for consideration.
was hypothetically presented as
Highlights the hypothetical nature of the presentation, indicating it's a basis for further investigation.
FAQs
How can I use "was initially hypothesized to" in a sentence?
You can use "was initially hypothesized to" to introduce a concept or theory that was originally proposed but may have been later disproven or modified, such as: "The treatment "was initially hypothesized to" reduce inflammation, but subsequent studies showed no significant effect".
What are some alternatives to "was initially hypothesized to"?
Alternatives include "was originally theorized to", "was first thought to be", or "was at first assumed to", depending on the context and the degree of certainty in the original proposition.
Is it better to say "was initially hypothesized to" or "is hypothesized to"?
"Was initially hypothesized to" indicates a past hypothesis, while "is hypothesized to" suggests a current hypothesis. Use "was initially hypothesized to" when discussing something that has been tested or reconsidered.
What's the difference between "was initially hypothesized to" and "was initially suggested to"?
"Was initially hypothesized to" implies a formal proposition based on some preliminary evidence, whereas "was initially suggested to" indicates a less formal, more tentative idea or possibility.
Editing plus AI, all in one place.
Stop switching between tools. Your AI writing partner for everything—polishing proposals, crafting emails, finding the right tone.
Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Source & Trust
83%
Authority and reliability
4.1/5
Expert rating
Real-world application tested