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Justyna Jupowicz-Kozak

CEO of Professional Science Editing for Scientists @ prosciediting.com

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was initially hypothesized to

Grammar usage guide and real-world examples

USAGE SUMMARY

"was initially hypothesized to" is a grammatically correct phrase and can be used in written English.
Example: The new treatment was initially hypothesized to be effective, but further research showed inconsistent results.

✓ Grammatically correct

Science

Human-verified examples from authoritative sources

Exact Expressions

5 human-written examples

Caveolin-1 was initially hypothesized to be a tumor suppressor in breast cancer [ 13].

Clonal expansion was initially hypothesized to be driven by a selective advantage for deleted mtDNA species over wild-type mtDNA molecules based upon replicative turnover (9).

Combat-related stress was initially hypothesized to be one of the factors responsible for the illnesses afflicting Gulf War veterans [ 177]; as a result, it was one of the few factors surveyed by all of the studies.

Initial measures of serum noradrenaline verified an inverse relation between serum levels and mortality, which was initially hypothesized to be a hormonal marker of hemodynamic stress, and later with the appreciation of the value of beta blockers to improve morbidity and mortality in heart failure, felt to itself be a mediator of the increased mortality rates [ 47, 48].

The T-to-C substitution was initially hypothesized to create an Sp-1 binding site, which could lead to up-regulation of transcriptional activation of the variant allele and higher activity of the enzyme [ 8, 9], but this was not observed in experimental studies [ 10- 12].

Human-verified similar examples from authoritative sources

Similar Expressions

55 human-written examples

Neighbors were initially hypothesized to be good key informants on the grounds of the close proximity of living quarters in camps for refugees and for internally displaced persons (IDPs) that generally are present in conflict-affected settings.

These compounds were initially hypothesized to inhibit the enzymes through the previously described nucleophilic attack/elimination/Lössen rearrangement reported by Groutas et al. for the structurally similar succinamide inhibitors of elastase.

This is contrary to what was initially hypothesized and what NGO reports and media stories would lead readers to believe.

In contrast to what was initially hypothesized, the evolution of pathogenic bacteria, that are specialized bacteria of particular interest to humans [ 50], consists mainly of gene losses [ 10, 51, 52].

Based on this information, it was initially hypothesized that dimorphism in cassava could be due to unreduced pollen grains.

Science

AoB PLANTS

It was initially hypothesized that addition of FL treatment expression data to the training compendium could also minimize background gene-gene interactions specific to FL's effects.

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Expert writing Tips

Best practice

Use "was initially hypothesized to" when describing an early-stage hypothesis that has since been tested or revised. This emphasizes the evolution of understanding.

Common error

Avoid presenting information that "was initially hypothesized to" be true as current fact without providing updated evidence or acknowledging the shift in understanding. Always clarify whether the initial hypothesis was supported or refuted by subsequent research.

Antonio Rotolo, PhD - Digital Humanist | Computational Linguist | CEO @Ludwig.guru

Antonio Rotolo, PhD

Digital Humanist | Computational Linguist | CEO @Ludwig.guru

Source & Trust

83%

Authority and reliability

4.1/5

Expert rating

Real-world application tested

Linguistic Context

The phrase "was initially hypothesized to" functions as a reporting verb phrase. It introduces a hypothesis that was proposed at an earlier stage. This type of construction is common in scientific and academic writing to describe the evolution of understanding.

Expression frequency: Rare

Frequent in

Science

80%

News & Media

10%

Formal & Business

10%

Less common in

Encyclopedias

0%

Wiki

0%

Reference

0%

Ludwig's WRAP-UP

In summary, "was initially hypothesized to" is a phrase used to introduce early-stage hypotheses, predominantly in scientific and academic writing. As Ludwig AI correctly points out, the phrase is grammatically sound and serves to contrast past assumptions with present knowledge. It is less common in informal contexts and should be used when precision and a formal tone are required. Remember to clarify whether the initial hypothesis was supported or refuted by subsequent research to avoid misleading your audience. Alternatives such as ""was originally theorized to"" or ""was first thought to be"" can be used depending on the context.

FAQs

How can I use "was initially hypothesized to" in a sentence?

You can use "was initially hypothesized to" to introduce a concept or theory that was originally proposed but may have been later disproven or modified, such as: "The treatment "was initially hypothesized to" reduce inflammation, but subsequent studies showed no significant effect".

What are some alternatives to "was initially hypothesized to"?

Alternatives include "was originally theorized to", "was first thought to be", or "was at first assumed to", depending on the context and the degree of certainty in the original proposition.

Is it better to say "was initially hypothesized to" or "is hypothesized to"?

"Was initially hypothesized to" indicates a past hypothesis, while "is hypothesized to" suggests a current hypothesis. Use "was initially hypothesized to" when discussing something that has been tested or reconsidered.

What's the difference between "was initially hypothesized to" and "was initially suggested to"?

"Was initially hypothesized to" implies a formal proposition based on some preliminary evidence, whereas "was initially suggested to" indicates a less formal, more tentative idea or possibility.

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Source & Trust

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Authority and reliability

4.1/5

Expert rating

Real-world application tested

Most frequent sentences: