Sentence examples for viral persistent from inspiring English sources

Our hypothesis that CD4+ T cells specific for herpes viral persistent antigens are more effectively restimulated by activated DCs, especially in the setting of limiting amounts of antigen, requires experimental validation.

To understand the viral persistent state in Sockeye Salmon we profiled the transcriptome to evaluate the host response in asymptomatic carriers and to determine what effects (if any) IHNV exposure may have on subsequent virus challenges.

Recent advances in HPV-induced cervical precancerous lesions highlight that different pathways of HPV infection (i.e., viral persistent, transient or latent infection, productive or permissive infection) may or may not progress to a "transforming infection," with risk of developing high grade squamous intraepithelial lesion and consecutive invasive cancer [ 40].

Thus, taking advantage of the hydrodynamic injection and clinical LAM-resistant data, we successfully established the LAM-resistant mouse models by introducing HBV DNA carrying double or triple LAM-resistant mutations into the tail vein of NOD/SCID mice, which is lack of functional T/B cells and beneficial to viral persistent replication.

As a pro-survival stragtegy, autophagy may help keep alive those virally infected cells, allowing persistent viral replication.

Moreover the down-regulation of cholesterol biosynthesis genes has been observed in both acute and persistent viral infections and is believed to restrict viral assembly through reduced cholesterol reserves [ 48, 78].

Nonetheless, when left unattended, a persistent viral infection combined with a strong and constitutive expression of viral oncoproteins E6 and E7 are highly inductive steps towards the malignant transformation of cervical epithelium [ 5].

They define persistent viral infections as infections in which the virus undergoes continuous viral replication while latent infections are defined as a "dormant" state during which replication is minimized or ceased.

Studies conducted to elucidate the immune factors involved in the effective generation and regulation of anti-viral CD8+ T cells to liver infections will greatly improve treatment strategies against persistent viral infections.

The sources of chronic immunologic stimulation in HIV are multiple and can include persistent viral replication, effects of circulating HIV proteins and virus like particles, opportunistic infections, and reactivation of other latent viral infections.

Dr. Bruce Chesebro, chief of the Laboratory of Persistent Viral Diseases at the federal Rocky Mountain Laboratories, said the experiment showed that the prion produced something in the mice.