These data indicate the tight balance between host and virus during persistent infection and the functional flexibility of the "inflated" CD8+ T cell responses during persistent infection.
We needed to concentrate on these lowland areas where the virus was persistent.
In its natural mammalian hosts, the Warthog and Bushpig, however, the virus is persistent, non-pathogenic and transmitted by an invertebrate vector, the soft tick.
In a second study, Herrera et al. explored the role of contingency in the coevolutionary process between cells and Foot-and-mouth disease virus during persistent infections [ 22].
Cell-mediated memory immune responses to viral antigens are important for protection against viruses causing persistent or acute infections.
Specifically, chronic viral infections that establish latency (e. g., the herpes viruses) cause persistent antigenic stimulation to T cells.
Persistent respiratory tract infection is common, with failure to clear viruses accompanying persistent bronchiolitic-like signs.
This may be causally linked to virus-induced persistent plastic chromatin deformations.
Downregulation of cell surface antigens provides a means of long-term survival of viruses and persistent infection.
