Exact(2)
Neutral variant: a variant that does not alter the function of a gene or confer any influence on the fitness of a gene.
AD is the first complex disorder for which a gene was identified through an association with a DNA variant, a variant in the APOE gene whose effect has been consistently observed since.
Similar(6)
A bioinformatic survey of human HBP/SLBP sequences led to the identification of two alternatively spliced variants; a variant that lacks exon 3 and one that lacks exon 2 out of a total of eight exons.
We identified several variants of the Beijing strain family; 2 isolates for variant B; 6 isolates for variant A, and 1 isolate for variant C [ 15].
Furthermore, the qualitative presence of either variant A or either variant E presented a significant correlation with metastasis (p = 0.043, Table 6 right).
The promoter regions (variant A, chr17:21,190,566–21,191,461 and variant B, chr17: 21,187,213–21,188,230, NCBI build 37.1, UCSC Genome Browser) were cloned into the promoterless PGL3-basic vector (Promega, Madison, WI, USA).
An interesting finding was made considering the two naturally occurring Bos d 5 variants, A and B. These variants differ at positions 64 (Asp/Gly) and 118 (Val/Ala).
In the African population the most common deficient variant is the G6PD A- variant.
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