Sentence examples for mutation a mutation from inspiring English sources

The additional observation that various phenotypes must be acquired suggests multiple mutations with no clonal expansion or a mutator mutation (a mutation that generates more mutations) coupled with clonal expansion [ 41].

Case 6, in addition to mutation 985A>G, carried the 347G>A mutation, a mutation previously described as severe [14], [16].

In addition to mutation 985A>G, one MCADD patient was carrier of the 347G>A mutation, a mutation previously described as severe [14], [16], this again is in excellent agreement with a low residual MCAD activity of 1.1%.

In this study we report for the first time of symptomatic GII.4 NoV infection of an individual homozygous for the G428A nonsense mutation, a mutation that previously has been shown to provide complete protection from authentic GII.4 NoV disease [19], [21].

Gene has Mutation: A mutation occurs in or near a gene, usually at a given position.

Mutation: A mutation is an alteration (deletion, insertion, substitution) of nucleotides (DNA, RNA) or amino acids (Protein).

Heterozygotes, whose red blood cells contain both HbA and HbS, are so strongly protected from malaria 19 20 that the global distribution and the frequency of the βS-mutation a mutation now strongly reflects the historic incidence of death from malaria.

Linkage and molecular genetic analyses, however, revealed two independent mutations: a mutation in one MMR gene (MSH2) and in one BC susceptibility gene (BRCA2).

If the presence of mutation A (allele fraction >5%) predates that of mutation B, mutation A is considered earlier than mutation B (Author response image 5).

At some time during the acquisition of these initial D mutations, a somatic mutator mutation may occur.

Concerning the high rate of mutations it must be differentiated which mutation is causative in the disease (driver mutation) and which is only a bystander mutation (passenger mutation).