up to a dose of

USAGE SUMMARY

The phrase "up to a dose of" is correct and usable in written English.
It can be used when discussing the maximum amount of a substance, typically in a medical or scientific context. Example: "The medication can be administered up to a dose of 500 mg per day."

✓ Grammatically correct

Science

Human-verified examples from authoritative sources

Exact Expressions

60 human-written examples

Gamma irradiation up to a dose of 10 kGy did not significantly alter the microbial population.

Advances in Space Research

This process lasts up to a dose of 8 × 1017 D/cm2.

Nanoscale Research Letters

The intensity of the peak increases up to a dose of 1 × 1017 D/cm2 (see Fig. 8).

Nanoscale Research Letters

In case of AV7 dye, removal increased up to a dose of 10 g/L with maximum removal of 75%.

Applied Water Science

The samples were irradiated by low-energy (1 10 keV), pulsed (20 ns) electron beam up to a dose of 6.2×1015 cm−2.

Surface and Coatings Technology

For irradiations performed with low-energy ions in the Sn regime, only the anion-deficient fluorite phase is formed up to a dose of 40 dpa.

Acta Materialia

Eurofer97 and F82H-mod specimens have been neutron-irradiated in the High Flux Reactor at Petten (HFR) up to a dose of 15 dpa at 250 450 °C.

Journal of Nuclear Materials

Acute toxicity studies showed that the total extracts of the plant are nontoxic up to a dose of 3 g/kg.

Pharmacognosy Journal

Our results demonstrate that VEDVDox, up to a dose of 5 × 109 VEDVDox weekly, is well tolerated in patients with recurrent GBM.

Journal of Clinical Neuroscience

Second, the bcc solid solution transformed into an amorphous state upon further irradiation up to a dose of 8×1015 Xe+/cm2.

Journal of Alloys and Compounds

The treatment was well tolerated up to a dose of 1000 kBq/kg with no signs of acute or subacute toxicity observed.

Translational Oncology

Expert writing Tips

Best practice

When using "up to a dose of", ensure the context clearly defines what is being measured (e.g., mg/kg, dpa) to avoid ambiguity. For example, specify "up to a dose of 2000 mg/kg body weight" for clarity.

Common error

Avoid using "up to a dose of" without specifying the units or context. For instance, stating "the drug is safe up to a dose" is vague. Always include the specific measurement, like "the drug is safe up to a dose of 50 mg daily".

Linguistic Context

The phrase "up to a dose of" functions as a prepositional phrase that modifies a noun or verb, specifying the maximum amount or limit of a substance, typically in medical or scientific contexts. Ludwig AI confirms that this phrase is correct and usable in written English.

Expression frequency: Very common

Frequent in

Science

100%

Less common in

News & Media

0%

Formal & Business

0%

Academia

0%

Ludwig's WRAP-UP

In summary, "up to a dose of" is a prepositional phrase commonly used in scientific and medical contexts to specify the maximum or threshold amount of a substance. Ludwig AI confirms its correctness and usability. It is crucial to provide units of measurement (e.g., mg/kg) to avoid ambiguity. Its usage is predominantly formal, appearing in scientific journals and research papers. The phrase effectively communicates the upper limit of a dosage, ensuring clarity and precision in scientific and medical discourse. The prevalence of this phrase in scientific sources indicates its importance in conveying precise quantitative information.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

reaching a maximum dosage of

Replaces "up to" with "reaching a maximum" for emphasis on attainment.

not exceeding a dosage of

Uses a negative constraint rather than a positive limit.

with a dosage limit of

Rephrases using "limit" as a noun to indicate the maximum allowable amount.

at a maximum dosage of

Focuses on the maximum dosage as a point or level.

to a maximum of

Simplifies the phrase, focusing on the maximum quantity.

up to a maximum level of

Adds emphasis on the level being the maximum.

peaking at a dosage of

Emphasizes the peak or highest point of the dosage.

with a ceiling of

Uses 'ceiling' to metaphorically represent an upper limit.

the maximum dose being

Inverts the sentence structure to highlight the dose as the subject.

limited to a dosage of

Highlights the restricted aspect of the maximum dosage.

FAQs

How do I use "up to a dose of" in a sentence?

Use "up to a dose of" to specify the maximum amount of a substance that can be administered or tolerated. For example, "The treatment was well tolerated "up to a dose of" 1000 kBq/kg with no signs of acute or subacute toxicity observed."

What are some alternatives to "up to a dose of"?

You can use alternatives such as "not exceeding a dose of", "maximum dose of", or "with a dosage limit of" depending on the context. For example, "The medication can be administered "not exceeding a dose of" 500 mg per day."

Is it correct to say "to a dose of" instead of "up to a dose of"?

While "to a dose of" might be grammatically correct in some contexts, "up to a dose of" is more precise when specifying a maximum limit or threshold. Consider, "The intensity of the peak increases "up to a dose of" 1 × 1017 D/cm2" versus "The intensity of the peak increases to a dose of 1 × 1017 D/cm2".

What's the difference between "up to a dose of" and "at a dose of"?

"Up to a dose of" indicates a maximum or limit, while "at a dose of" specifies a particular quantity or level. For instance, "Telatinib is safe and well tolerated "up to a dose of" 1500 mg BID continuous dosing", compared to "The drug was effective "at a dose of" 100 mg daily".