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Justyna Jupowicz-Kozak

CEO of Professional Science Editing for Scientists @ prosciediting.com

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underlying defects

Grammar usage guide and real-world examples

USAGE SUMMARY

The phrase "underlying defects" is correct and usable in written English.
It can be used to refer to fundamental issues or flaws that are not immediately visible but affect the overall quality or functionality of something. Example: "The inspection revealed several underlying defects in the building's structure that needed to be addressed before proceeding with renovations."

✓ Grammatically correct

Science

Medicine

Genetics

Oncology

Human-verified examples from authoritative sources

Exact Expressions

20 human-written examples

It is certainly too much to request that pre-, pror, or synbiotics shall make a difference in such conditions unless the underlying defects in metabolism and immune functions are corrected.

However, these studies were qualitative and did not address the cellular mechanisms underlying defects.

Human cancers exhibit genomic instability and an increased mutation rate due to underlying defects in DNA repair.

The high variability of the floral aberrations indicated that they are the result of underlying defects in the meristem.

It was therefore postulated that underlying defects predisposing for AD may reside in the HSCs and that HSCT could be an effective treatment of AD.

These defects may be due to underlying defects in the differentiation of the command interneurons that coordinate forward and backward motility [ 26, 54].

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Human-verified similar examples from authoritative sources

Similar Expressions

40 human-written examples

The treatments described above are all aimed at managing the downstream consequences of defective CFTR function and improving symptoms rather than tackling the underlying defect.

Its underlying defect is the deficient production of adult hemoglobin (hemoglobin A).

Because the underlying defect of the lower esophageal sphincter (LES) was not repaired, surgery failed to control symptoms, and the procedure was not widely embraced.

Science & Research

Nature

Guided by mechanistic understanding of the underlying defect, it might be possible to correct this by using small molecules that weaken or strengthen dynein.

Science & Research

Nature

Despite prolonging survival and improving quality of life, these approaches fell short of the ultimate goal to remedy the underlying defect of the disease.

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Expert writing Tips

Best practice

When discussing complex systems or processes, use "underlying defects" to highlight fundamental issues that are not immediately obvious.

Common error

Avoid using "underlying defects" when simpler terms like "problems" or "flaws" would suffice. The phrase is best suited for situations requiring a deeper level of analysis.

Antonio Rotolo, PhD - Digital Humanist | Computational Linguist | CEO @Ludwig.guru

Antonio Rotolo, PhD

Digital Humanist | Computational Linguist | CEO @Ludwig.guru

Source & Trust

81%

Authority and reliability

4.5/5

Expert rating

Real-world application tested

Linguistic Context

The phrase "underlying defects" functions as a noun phrase, typically serving as the object or subject complement in a sentence. It identifies fundamental flaws that cause broader issues. Ludwig AI confirms its correct usage in various contexts.

Expression frequency: Common

Frequent in

Science

60%

Academia

20%

News & Media

10%

Less common in

Formal & Business

5%

Encyclopedias

3%

Reference

2%

Ludwig's WRAP-UP

The phrase "underlying defects" refers to fundamental flaws that are not immediately obvious but affect the overall system or entity. As Ludwig AI indicates, its usage is grammatically correct, mostly appearing in scientific and academic contexts. Alternatives include "fundamental flaws" or "root causes". The phrase is most effective in formal settings where a deeper analysis of problems is required, and is best avoided in simpler contexts where more common terms suffice. Its primary function is to identify the fundamental issues prompting further action, and its frequency across sources is categorized as common.

FAQs

How can I use "underlying defects" in a sentence?

You can use "underlying defects" to describe fundamental flaws or problems that are not immediately visible, as in, "The analysis revealed several "underlying defects" in the system's design".

What are some alternatives to "underlying defects"?

Some alternatives include "fundamental flaws", "root causes", or "basic deficiencies" depending on the specific context.

Is "underlying defects" a formal or informal phrase?

"Underlying defects" is generally considered a more formal phrase, suitable for academic, scientific, or professional contexts. Simpler terms might be preferred in informal settings.

In what contexts is "underlying defects" most appropriately used?

This phrase is often used in scientific, medical, and technical contexts to describe fundamental problems affecting the functionality or integrity of a system or process.

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Source & Trust

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Authority and reliability

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Real-world application tested

Most frequent sentences: