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We found Tat-Smad7 treatment significantlly reduced ulcer incidence and sizes.
Published pressure ulcer incidence and prevalence figures in the paediatric population vary widely.
Pressure ulcer incidence is widely accepted as an indicator for the quality of care.
Objective: To investigate the relation between pressure ulcer incidence and buttock-wheelchair seat cushion interface pressure measurements.
Namely, ulcer incidence was 16.6% for plaques causing 50 69% stenosis, 22.6% for 70 84% stenosis and 33.4% for stenosis >85% [7].
Brienza DM, Karg PE, Geyer MJ, Kelsey S, Trefler E. The relationship between pressure ulcer incidence and buttock-seat cushion interface pressure in at-risk elderly wheelchair users.
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This hypothesis is also supported by a study that found a higher pressure ulcers incidence in patients submitted to spinal surgeries [ 23].
In addition, it should be noted that neurosurgeries in the ventral position include spinal surgeries, and this could have determined the higher pressure ulcers incidence observed [ 22].
No differences were found in the lesion distribution in patients younger than 65 (not a statistically comparable number), while in the others (patients over 65 years old) there was a clear difference of site: in naturopathic patients the ulcers incidence were more in the plantar surface of the foot (52.1%), especially in metatarsal heads area (49.6%).
Although most patients with acute peritonitis (94%) did not demonstrate clinical signs of ulcer, the incidence of stress ulcer was significantly higher (32% in nonsurvivors).
Therefore, the objective of the present study was to compare in an intention-to-treat analysis the effect of pressure-improved custom-made footwear with that of usual care (i.e., nonimproved custom-made footwear) on plantar foot ulcer recurrence incidence in 18 months.
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