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Wilhelm Körner, (born April 20 , 1839 Kassel, Hesse-Kassel [Germany] died March 28 , 1925 Milan, Italy) German organic chemist who in 1874 showed how to determine the relative positions of two substituents, such as methyl, on the benzene ring.

April 20 , 1839Kassel, Germany March 28 , 1925Milan, Italy Wilhelm Körner, (born April 20 , 1839 Kassel, Hesse-Kassel [Germany] died March 28 , 1925 Milan, Italy) German organic chemist who in 1874 showed how to determine the relative positions of two substituents, such as methyl, on the benzene ring.

The relative positions of the two substituents are identified by the signs of their x coordinates.

The positions of the remaining two substituents are then identified by the signs of their x coordinates.

This approach has been extended to the substituted derivatives of the closo-decaborate anion with two substituents [B10H8X2]2−.

Compounds with these two substituents are the most potent compounds in this series with good selectivity over related serine proteases.

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In this compound the central carbon is trivalent since it is combined with three substituents instead of four, and its unshared electron is represented by a dot.

In this case, the position information of four substituents of chiral center was predefined.

LINDES 2.8 does not determine the stereochemistry of chiral centers or double bonds with fewer than four substituents.

The MCDL can also specify chirality of atomic centers with only three substituents in those cases where the fourth substituent position is occupied by an electron pair.

Thus, of the four substituents attached to the chiral atom in lactic acid, the terminal atom H has the lowest priority.

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