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Generally, members of the dynamin protein family are known regulators of vesicle trafficking implicated in constricting and severing membrane tubules [21].
The finding that SNAT-2 protein expression was decreased in the MVM but not in total placental homogenate strongly suggests that the observed responses are caused by changes in SNAT-2 plasma membrane trafficking, implicating the inhibition of mTORC1 and mTORC2 as the mechanism underlying the decreased MVM SNAT-2 expression in IUGR.
The reported findings may be influenced by the inclusion of susceptible individuals, but the large risks uncovered here and in the few other studies focused on traffic implicate TRAP as a risk to public health.
As the disruption of axonal trafficking is implicated in neuronal degeneration and is observed in diseases like Alzheimer's disease, Huntington's disease, spinobulbar muscular atrophy, Charcot-Marie-Tooth disease, etc. [22] [26], the influence of genetic impairment of oxidative phosphorylation on axonal transport is especially relevant.
Further, if fetomaternal cell trafficking is implicated in the etiology of AID after pregnancy, we expected the highest increase in AID diagnosis following (i) CS, due to increased fetomaternal hemorrhage, and (ii) abortion, as fetal loss has been shown to be the only pregnancy complication significantly influencing microchimerism.
A time-based traffic model implicates that the number of currently active users is independent of the perceived data rates.
One of the environmental impacts of aviation is that persistent contrails can form into large mats of cirrus, and increased air traffic has been implicated as one possible cause of the increasing frequency and amount of cirrus in Earth's atmosphere.
Our findings emphasize the importance of defense responses and cytoskeletal, mitochondrial and proteasomal dysfunction, reflect reduced neuronal maintenance and vesicle trafficking , and implicate impaired ion homeostasis and glycolysis in ALS pathogenesis.
Despite having identified multiple membrane trafficking regulator proteins implicated in the removal of MHC-I from the cell surface, it remains unknown what cellular compartments are used by Nef during this process precluding our understanding of the pathway subverted by HIV-1 to evade immune surveillance.
"But the disappearance of files from human trafficking cases that implicated DynCorp personnel, the abrupt and unexplained cancellation of legitimate human rights investigations, men from around the globe getting away with buying and raping teenage girls – these are not isolated incidents and cannot be dismissed as the actions of rogue individuals".
There is mounting evidence that synaptic vesicle trafficking pathways are implicated in PD mechanisms.
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The phrase "traffic implicated" functions as a descriptive element, often acting as an adjective phrase modifying a noun. It suggests that traffic is connected to or involved in a particular event, situation, or outcome. Ludwig AI explains that this phrase is not considered as standard in written English.
Expression frequency: Rare
