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Based on 13C isotopic dilution in organic matter extracts and their 13C-cross polarization magic angle spinning (CPMAS -NMR speCPMAS -NMReferential decreaspectraydrophobicity was assessed when preferential forestedecreasetivated sofl, thydrophobicitytiating that accumulation of organic matter in soil proceeded by stabilization of hydrophobic molecular associations [9],[10].

Therefore, the mathematical prediction made by the model agrees very closely with the biological data, thereby substantiating the physical meaning of the model.

The lactate biosensor was used for the electrochemical detection of sweat lactate, thereby substantiating its utility for the noninvasive assessment of lactate levels and degree of physical exertion.

In contrast, a statistically significant reduction in the expression of these genes was seen in Smad-3 depleted cells, thereby substantiating the dominant role of Smad-2.

This dose leads to significantly lower serum testosterone and inhibin-B levels which in turn give rise to higher serum LH and FSH concentrations, thereby substantiating that the pituitary function is unimpaired.

Along the same lines, indices of RH could be used to test whether the therapeutic intervention is having the intended physiologic effects and clinical benefits, thereby substantiating a clinically relevant mechanistic pathway.

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The current data support an etiological role for altered oestrogen signalling in osteoarthritis and thereby substantiates the link between estradiol and the development of osteoarthritis.

This thereby substantiated concerns in earlier reports that this estimation of LV filling pressure may be a less sensitive measure of diastolic function, especially in metabolic disease with its predominantly mild degree of diastolic dysfunction [ 18, 29].

We conclude that fibrinogen (citrullinated or not) can induce proliferation of RA T cells, thereby further substantiating its pathogenic relevance.

However, no typical spin systems for saccharide-like structures were detected in TOCSY spectra for the F1 size fraction (data not shown), thereby failing to substantiate their presence.

Although the role of c-CBL in the negative regulation of RTKs is well substantiated, thereby suggesting that it is a natural tumor suppressor, studies in cancer cells have revealed both tumor suppressor and tumor promoting activities depending on the type of c-CBL mutation and the number of alleles at the c-CBL locus [24].

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