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To our best knowledge, all of these 26 miRNA candidates have not been reported thus far in rice or in other species and hence substantiating their novelty.
In the present patient series, membrane expression of pHER3 did not add prognostic information to the current clinical parameters, hence substantiating that HER2 is the dominant HER receptor and that the function of HER3 is primarily to act as a co-activator of HER2.
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This effect of thermodynamic non-ideality implicates the existence of a substrate-induced conformational change that is governed by a minor volume decrease and a very small isomerization constant; and hence, substantiates earlier inferences that the rate-determining step in pyruvate kinase kinetics is isomerization of the ternary enzyme product complex rather than the release of products.
This study hence experimentally substantiates the "valve" concept in fracture mechanics.
However, some of these cytokines are known to work in an agonist antagonist interaction, hence further substantiating that the co-culture of ECs with ASCs leads to physiological, controlled vascular network formation [ 33].
Hence, to further substantiate the possible role of JC15 in activating MPTP through CypD, we contemplated whether lower levels of JC15 could rescue deleterious effects of elevated CypD.
14 Hence, the present study substantiated that the once-daily rivastigmine patch offers a user-friendly treatment alternative to achieve higher treatment compliance in patients with mild-to-moderate AD.
First, we found no published data describing and substantiating the specific time-points to assay the dynamics of hematopoiesis in response to gastrointestinal tract delivery of a drug – hence we were free to choose the control points.
Hence, our results have to be substantiated by functional and immunohistological investigations on hBDs in patients with BCC.
Hence, the influence of personality traits on pain can be substantiated by mechanisms involving the descending control of pain; therefore, an anxious and pain-vigilant personality might arise from less effective intrinsic regulation of nociception.
Hence, sonoelastography could quantify the magnitude of intralesional microcirculation or neoangiogenesis, and substantiate the consistency of testicular masses.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com