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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com
that is most significant
Grammar usage guide and real-world examplesUSAGE SUMMARY
The phrase "that is most significant" is correct and usable in written English.
You can use it to emphasize the importance or relevance of a particular point or detail in a discussion or argument. Example: "In this study, the data collected from the participants revealed several trends, but the increase in engagement levels is that which is most significant."
✓ Grammatically correct
Science
News & Media
Encyclopedias
Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Human-verified examples from authoritative sources
Exact Expressions
8 human-written examples
It is the interior design that is most significant, however.
Encyclopedias
Yet it isn't technique or the startling image that is most significant about this company from Guangzhou (formerly Canton).
News & Media
However, it is the attitude that comes with war that is most significant, the placing of personal ambitions and strategies for power over the progression of the lives of your people.
News & Media
However, it was the newness and innovation which Newman encouraged in his drama output that is most significant: his concentration on the potential of television as television, for a mass not a middlebrow audience".
Wiki
It is this secondary loss of cones that is most significant clinically because cones are required for high acuity, color, and most daylight vision.
Science
The replacement of the long arginine side chain with the more compact proline opens one side of the Phe recognition pocket and also appears to induce a conformational change in the α1′−β1′ loop that is most significant near Asn1774.
Science
Human-verified similar examples from authoritative sources
Similar Expressions
51 human-written examples
There are two aspects of Ad Manager that are most significant: First, It is completely free to site owners.
News & Media
We can't help but enjoy those games that are most significant".
News & Media
"We can't help but enjoy those games that are most significant," Miles said.
News & Media
He isolated over 100 genes that regulate various phases of the cell cycle, but the one that was most significant was called cdc28.
News & Media
Almost a quarter of voters said strong moral character was the quality that was most significant; more than a third of them backed Mr. Santorum.
News & Media
Expert writing Tips
Best practice
In persuasive writing, use "that is most significant" to emphasize the point that should resonate most with your audience and support your central claim effectively.
Common error
Avoid using "that is most significant" in sentences where simpler phrasing would suffice. Instead of saying "For me, that is most significant", consider using a more direct alternative such as "That matters most to me."
Source & Trust
84%
Authority and reliability
4.1/5
Expert rating
Real-world application tested
Linguistic Context
The phrase "that is most significant" functions as a predicate adjective, emphasizing the importance or impact of a particular subject. As Ludwig AI confirms, this phrase is a valid and usable construction in English. It serves to highlight what is paramount.
Frequent in
Science
62%
News & Media
25%
Encyclopedias
13%
Less common in
Formal & Business
0%
Wiki
0%
Reference
0%
Ludwig's WRAP-UP
In summary, the phrase "that is most significant" serves to emphasize the paramount importance or impact of something within a specific context. As Ludwig AI confirms, it’s grammatically correct and usable, although it is more common in scientific and news-related sources. The phrase functions as a predicate adjective, drawing attention to what is truly essential. Remember to use it judiciously, favoring simpler phrasing when appropriate, and ensure that it adds clarity and emphasis to your writing. Alternatives such as "that is most important" or "that is paramount" can be used to achieve a similar effect.
More alternative expressions(6)
Phrases that express similar concepts, ordered by semantic similarity:
that is of greatest importance
Replaces "significant" with "importance", emphasizing the high value or crucial nature of something.
that is paramount
Uses "paramount" to indicate the supreme importance or dominance of something.
that is of primary concern
Focuses on the level of worry or interest attributed to something.
that is the key thing
Highlights the most important aspect or element of a situation.
that is the crux of the matter
Identifies the decisive or critical point of an issue.
that is fundamentally important
Emphasizes the basic or essential nature of something's importance.
that carries the most weight
Highlights that something has the biggest influence or impact.
that is centrally important
Emphasizes the central role or importance of something.
that is preeminently vital
Uses "preeminently" to convey exceptional importance or necessity.
that holds the utmost significance
Indicates that something possesses the highest degree of importance or meaning.
FAQs
How can I use "that is most significant" in a sentence?
You can use "that is most significant" to emphasize the most crucial or impactful aspect of something. For example, "Among all the findings, the correlation between exercise and mental health is "that is most significant"."
What are some alternatives to "that is most significant"?
Some alternatives include "that is most important", "that is paramount", or "that is of greatest significance". The best choice depends on the specific context and the nuance you wish to convey.
What makes "that is most significant" different from "that is important"?
"That is important" indicates something of value, while ""that is most significant"" singles out the element of paramount importance among multiple factors. The latter emphasizes a greater degree of impact or relevance.
Is it acceptable to use "that is most significant" in formal writing?
Yes, ""that is most significant"" is appropriate for formal writing when you need to highlight the preeminent aspect of a topic. Ensure that its use adds clarity and emphasis to your argument.
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Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Source & Trust
84%
Authority and reliability
4.1/5
Expert rating
Real-world application tested